Journal of Postgraduate Medicine
 Open access journal indexed with Index Medicus & ISI's SCI  
Users online: 949  
Home | Subscribe | Feedback | Login 
About Latest Articles Back-Issues Article Submission Resources Sections Etcetera Contact
 
  NAVIGATE Here 
 ::   Next article
 ::   Previous article
 ::   Table of Contents

 RESOURCE Links
 ::   Similar in PUBMED
 ::  Search Pubmed for
 ::  Search in Google Scholar for
 ::   Citation Manager
 ::   Access Statistics
 ::   Reader Comments
 ::   Email Alert *
 ::   Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed3051    
    Printed115    
    Emailed3    
    PDF Downloaded0    
    Comments [Add]    

Recommend this journal


 

 ARTICLE
Year : 1976  |  Volume : 22  |  Issue : 2  |  Page : 94-99

Study of bioavailability of oral iron preparations


1 Clinical Pharmacology Unit and the Clinical Drug Trial Unit, Council of Scientific & Industrial Research, Department of Pharmacology, Seth G. S. Medical College, & K.E.M. Hospital, Parel, Bombay 400 012., India
2 Department of Medicine, K.E.M. Hospital, Bombay 400012., India
3 Department of Statistics, University of Bombay, Bombay., India

Correspondence Address:
Kusum C Gupta
Clinical Pharmacology Unit and the Clinical Drug Trial Unit, Council of Scientific & Industrial Research, Department of Pharmacology, Seth G. S. Medical College, & K.E.M. Hospital, Parel, Bombay 400 012.
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


PMID: 802126

Rights and PermissionsRights and Permissions

Two preparations o f oral iron, were evaluated in normal volun­teers and in patients of iron deficiency anemia. The study in 10 normal volunteers measured the bioavailability of the two prepa­rations. The study in 20 patients assessed the therapeutic equiva­lence and tolerance. In the volunteer study, serum iron levels at 4 and 8 hours were significantly higher with the iron vitamin-­mineral combination than with the plain iron. The AUC was also significantly higher. In patients there was no difference in the effect of the two formulations. With both there was a rapid rise in Hb, PCV and reticulocyte count in the first week, after that the rate of increase was slow. Both preparations were equally well tolerated.






[FULL TEXT] [PDF Not available]*


        
Print this article     Email this article

Online since 12th February '04
© 2004 - Journal of Postgraduate Medicine
Official Publication of the Staff Society of the Seth GS Medical College and KEM Hospital, Mumbai, India
Published by Wolters Kluwer - Medknow