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 ARTICLE
Year : 1978  |  Volume : 24  |  Issue : 3  |  Page : 171-176

Pharmacological Studies of p, N-(3, 4-Methylenedioxy phenyl) Benzoic Acid (RRL-1364) - Part-I


Department of Pharmacology, Seth G. S. Medical College, Parel, Bombay-400 012, India

Correspondence Address:
Sharadini A Dahanukar
Department of Pharmacology, Seth G. S. Medical College, Parel, Bombay-400 012
India
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Source of Support: None, Conflict of Interest: None


PMID: 722614

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Detailed pharmacological investigations of p-N-(3, 4-methylene dioxy phenyl) benzoic acid revealed marked hypotensive action which was dose dependent and most marked in cats; it was absent in rats. Atropine could block this hypotensive action, thus suggest­ing cholinomimetic mechanism. Further studies indicated that the hypotension produced was central and possibly medullary in origin.






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Online since 12th February '04
© 2004 - Journal of Postgraduate Medicine
Official Publication of the Staff Society of the Seth GS Medical College and KEM Hospital, Mumbai, India
Published by Wolters Kluwer - Medknow