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 ARTICLE
Year : 1979  |  Volume : 25  |  Issue : 1  |  Page : 52-56

Serum lactic dehydrogenase isoenzymes and serum hydroxy butyric dehydrogenase in myocardial infarction


Cordiovascular and Thoracic Centre, K.E.M. Hospital and Seth G.S. Medical College, Parel, Bombay 400012, India

Correspondence Address:
D S Kanekar
Cordiovascular and Thoracic Centre, K.E.M. Hospital and Seth G.S. Medical College, Parel, Bombay 400012
India
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Source of Support: None, Conflict of Interest: None


PMID: 458744

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Total serum lactate dehydrogenase activity in cases of myocar­dial infarct is difficult to interpret as abnormal values can occur in diseases of liver, kidney and skeletal muscle. The estimation of its isoenzymes is of better diagnostic help because of its tissue specificity. Serum LDH isoenzymes were studied in patients o f myocardial infarction and results are quantitated by densitometry. As LDH 1 represents serum hydroxybutyric dehydrogenase when 2-oxylbutyrate is used as substrate, serum hydroxybutyric dehydro­genase was also estimated in above patients. Greater specificity in diagnosis is achieved with SHBDH because of its myocardial nature and lower incidence of false positive results.






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Online since 12th February '04
© 2004 - Journal of Postgraduate Medicine
Official Publication of the Staff Society of the Seth GS Medical College and KEM Hospital, Mumbai, India
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