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  IN THIS Article
 ::  Introduction
 ::  Case report
 ::  Comment
 ::  Acknowledgements
 ::  References

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Year : 1982  |  Volume : 28  |  Issue : 2  |  Page : 120-122

Leiomyosarcoma of penis (a case report).







How to cite this article:
Jain S S, Vohra R R, Kohli P K, Bharti. Leiomyosarcoma of penis (a case report). J Postgrad Med 1982;28:120-2


How to cite this URL:
Jain S S, Vohra R R, Kohli P K, Bharti. Leiomyosarcoma of penis (a case report). J Postgrad Med [serial online] 1982 [cited 2019 Nov 17];28:120-2. Available from: http://www.jpgmonline.com/text.asp?1982/28/2/120/5580




  ::   Introduction Top

Leiomyosarcoma of penis is a rare tumour. Sixteen cases of histologically proven leiomyosarcoma of penis have so far been reported.[8]

  ::   Case report Top

R. L., a 55 year old male patient was admitted to the Institute hospital, with complaints of gradually increasing swelling at the tip of penis and difficulty in micturition for the last six months. Systemic examination revealed no abnormality. On local examination, glans penis was totally replaced by a firm, fungating, mass extending into the shaft [Fig. 1]. External urethral meatus was invaded by the growth. The corpus spongiosum was indurated; inguinal lymph nodes were not enlarged. Chest X-ray was normal. Wedge biopsy from the lesion revealed spindle cell sarcoma with a possibility of leiomyosarcoma.
Total amputation of penis and perineal urethrostomy was performed. Histopathology cofirmed the dignosis of leiomyosarcoma. Postoperative period was uneventful. At one and half year follow up, the patient is aymptomatic and there is no evidence of local or systemic disease.
Histology
Section showed a highly vascular tumour composed of spindle cells arranged in interlacing bundles with areas of haemorrhage and necrosis [Fig. 2]. Each cell showed enlongated eosinophilic cytoplasm, spindle shaped nucleus with open chromatin and blunted edges, and four to five mitotic figures per high power field. Interspersed with cellular areas were areas of myxoid degeneration. Tumour showed dense reticulin condensation and Masson's trichrome stain revealed mild to moderate collagen formation. Final histological diagnosis was leiomyosarcoma of the penis.

  ::   Comment Top

Leiomyosarcoma of penis may be superficial or deep. Superficial tumours arise from smooth muscle elements in superficial tissues of shaft of penis. Deep tumours arise from muscle fibres in corpora cavernosa, tend to invade urethra and metastasize early. The present case had a superficial tumour.
The treatment of choice is total amputation of penis. The results of local excision and radiotherapy are poor.[1]

  ::   Acknowledgements Top

We thank Dr. S. P. Kaushik for allowing us to publish this case.

  ::   References Top

1.Greenwood, N., Fox, H. and Edwards, E. C.: Leiomyosarcoma of the penis. Cancer, 29: 481-483, 1972.  Back to cited text no. 1    
2.McKenzie, P. R. and Ross, R. J. A.: Leiomyosarcoma of the penis, a report of a case. Brit. J. Surg., 56: 870-872, 1969.   Back to cited text no. 2    
3.Prabhakar, B. R., Sethi, R. S., Singh, H., Tung, B. S. and Prabhakar, H.: Leiomyosarcoma of penis, Ind. J. Canter, 12: 103-106, 1975.   Back to cited text no. 3    

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Online since 12th February '04
2004 - Journal of Postgraduate Medicine
Official Publication of the Staff Society of the Seth GS Medical College and KEM Hospital, Mumbai, India
Published by Wolters Kluwer - Medknow