Journal of Postgraduate Medicine
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 ORIGINAL ARTICLE
Year : 1990  |  Volume : 36  |  Issue : 4  |  Page : 194-8

Comparative evaluation of bone marrow aspirate particle smears, imprints and biopsy sections.


Department of Pathology, Dayanand Medical College and Hospital, Ludhiyana.

Correspondence Address:
B D Sabharwal
Department of Pathology, Dayanand Medical College and Hospital, Ludhiyana.

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Source of Support: None, Conflict of Interest: None


PMID: 0002132243

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Comparative evaluation of bone marrow aspirate particle smears, imprints and biopsy sections was done on 30 haematological problems. Core needle biopsy of the bone marrow is a safe and useful procedure. It is a valuable diagnostic aid for measurement of marrow cellularity, metastatic tumours and fibrosis. It should not be taken as a substitute for examination of the marrow by aspiration smear but is a complementary procedure which affords several advantages. Bone marrow biopsy was of maximum utility in myelofibrosis which was diagnosed on biopsy alone. There were three additional cases with normal bone marrow aspiration in which specific diagnosis could only be made from bone marrow biopsy sections. New methodologies i.e. plastic embedding and semi thin sections of undecalcified bone marrow, can be expected to improve the cytological details of tissue obtained by biopsy. Imprint preparations obtained from biopsy can be useful in patients of malignancy but we have found them to be of limited value except in cases of dry tap.






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Online since 12th February '04
2004 - Journal of Postgraduate Medicine
Official Publication of the Staff Society of the Seth GS Medical College and KEM Hospital, Mumbai, India
Published by Wolters Kluwer - Medknow