Journal of Postgraduate Medicine
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Year : 1992  |  Volume : 38  |  Issue : 3  |  Page : 109-11

MURCS association--a review of 7 cases.


Dept of Paediatrics, Seth GS Medical College, Parel, Bombay, Maharashtra.,

Correspondence Address:
P Mahajan
Dept of Paediatrics, Seth GS Medical College, Parel, Bombay, Maharashtra.

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PMID: 0001303407

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MURCS association (Mullerian hypoplasia/aplasia, renal agenesis and cervicothoracic somite dysplasia) is emerging as the second most frequent cause of primary amenorrhoea after Turner syndrome. Seven cases have been described and analysed. All cases had absence of uterus and tubes 85% had cervical spine abnormalities such as vertebral fusion, hypoplasia of vertebrae or butterfly vertebrae and short stature and 28% had renal agenesis or ectopy. The latter finding is in contrast to the reports in world literature where the frequency of renal agenesis is higher. There was no familial incidence in these seven cases lending credence to the belief that the association is essentially sporadic.






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Online since 12th February '04
2004 - Journal of Postgraduate Medicine
Official Publication of the Staff Society of the Seth GS Medical College and KEM Hospital, Mumbai, India
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