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Year : 1992  |  Volume : 38  |  Issue : 4  |  Page : 183-5

Relevance of plasma fibrinogen estimation in obstetric complications.

Dept of Gynaecology and Obstetrics, Seth GS Medical College, Parel, Bombay, Maharashtra.

Correspondence Address:
H Parasnis
Dept of Gynaecology and Obstetrics, Seth GS Medical College, Parel, Bombay, Maharashtra.

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Source of Support: None, Conflict of Interest: None

PMID: 0001307590

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We present a study of fibrinogen levels in 133 patients who were prone to develop disseminated intravascular coagulation as a result of an underlying complication of pregnancy such as abruptio placentae, pregnancy-induced hypertension, missed abortion, septic abortion, intrauterine fetal death, vesicular mole and amniotic fluid embolism. A high incidence of hypofibrinogenemia was found in cases of abruptio placentae (43.9%) and pregnancy-induced hypertension (25%). Hypofibrinogenemia occurred in 10% cases of intrauterine fetal death within 4 weeks of fetal demise. The use of this simple investigation makes possible the diagnosis of hemostatic failure and also helps to guide replacement therapy during the fibrinopenic state. There were 4 maternal deaths and 12 perinatal losses in this study.


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Online since 12th February '04
2004 - Journal of Postgraduate Medicine
Official Publication of the Staff Society of the Seth GS Medical College and KEM Hospital, Mumbai, India
Published by Wolters Kluwer - Medknow