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|Year : 1996 | Volume
| Issue : 1 | Page : 27
Plasmacytoma of scalp.
RR Vyas, SS Dixit, SS Singhal, JP Neema, UU Suryanarayan, HA Baboo
Department of Radiotherapy, Gujrat Cancer & Research Institute, Ahmedabad, Gujrat.,
R R Vyas
Department of Radiotherapy, Gujrat Cancer & Research Institute, Ahmedabad, Gujrat.
Source of Support: None, Conflict of Interest: None
An interesting case of plasmacytoma of the scalp is described. Extramedullary plasmocytoma of scalp is rarely reported. This patient was treated with external radiotherapy dose of which was 40 Gy/20 fraction. Disease responded very well to radiotherapy.
Keywords: Antineoplastic Agents, therapeutic use,Case Report, Chemotherapy, Adjuvant, Female, Human, Middle Age, Plasmacytoma, pathology,radiotherapy,Scalp, Skin Neoplasms, pathology,radiotherapy,
|How to cite this article:|
Vyas R R, Dixit S S, Singhal S S, Neema J P, Suryanarayan U U, Baboo H A. Plasmacytoma of scalp. J Postgrad Med 1996;42:27
Extramedullary solitary plasmacytoma is an uncommon presentation. Plasmacytoma of skin and subcutaneous tissue is a rare tumour. Only a few cases have been reported in the literature so far,.
A 55-year-old female reported at the Gujarat Cancer & Research Institute. She complained of a gradually increasing swelling over frontoparietal region of head of 6 months duration [Figure - 1]. On examination a rounded swelling of 8 x 10 cm size was palpable over frontoparietal region. It was non-tender and firm in consistency with restricted mobility. No lymphadenopathy or organomegaly was noted.
On investigations, X-ray skull showed erosion of outer table of frontal bone. Radiological skeletal survey was normal. Bence Jones proteins were negative in urine. Bone marrow examination showed no evidence of infiltration by plasma cells. Histopathological examination of punch biopsy obtained from the swelling revealed it to be plasmacytoma.
Local radiotherapy was given over the swelling by two tangential portals. A total tumour dose of 40 Gy was delivered in 20 fractions. There was a significant (> 50%) regression of the swelling at the end of radiation treatment. Patient was then referred for chemotherapy.
Extramedullary plasmacytoma is uncommon. In head and neck region, their frequency is about 0.5%. The tumour shows intense infiltration by plasma cells on histopathological examination.
The tumour is radiosensitive and responds to local radiotherapy. Most of the patients subsequently develop the features of multiple myeloma.
Plasmacytoma of skin were reported in a series of 8 cases by Torne et al. Subcutaneous plasmacytoma of breast region has also been reported  Plasmacytoma of scalp is probably the rarest occurrence. In this case, the tumour was subcutaneous in origin and was eroding the frontal bone.
| :: References|| |
Anderson PE. Extramedullary plasmacytomas. Acta Radiol (Stock) 1949; 32:365-374. |
|2.||Torne R, Su WPD, Winkelmann RK. Clinicopathologic study of cutaneous plasmacytoma. Int J Dermatol 1990; 29:562-566. |
|3.||Marino MJ. Plasmacytoma of the breast. Arch Pathol Lab Med 1984; 108:676-678. |
|4.||Mayr NA, Wen BC, Hussey DH. The role of radiation therapy in treatment of solitary plasmacytoma. Radiother Oncol 1990; 17:293-303.
[Figure - 1]
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