Journal of Postgraduate Medicine
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 UPDATE ARTICLE
Year : 2002  |  Volume : 48  |  Issue : 1  |  Page : 56-63

Allograft biopsies in management of pancreas transplant recipients.


Division of Transplantation Pathology, Department of Pathology, C903.1 Presbyterian University Hospital, University of Pittsburgh, Pittsburgh, PA 15213, USA. , USA

Correspondence Address:
P Randhawa
Division of Transplantation Pathology, Department of Pathology, C903.1 Presbyterian University Hospital, University of Pittsburgh, Pittsburgh, PA 15213, USA.
USA
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Source of Support: None, Conflict of Interest: None


PMID: 12082334

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Pancreatic transplantation is becoming increasingly accepted as a treatment modality for Type 1 diabetes mellitus. When allograft dysfunction is noted during follow up of patients, a biopsy is an extremely useful tool to diagnose various forms of rejection, and to rule out non-immunologic causes of graft malfunction, such as donor disease, ischaemic/preservation injury, vascular thrombosis, pancreatitis, post-transplant lymphoproliferative disease, technical complications and recurrence of diabetes mellitus. In addition to its role in establishing the primary diagnosis, a biopsy can grade the severity of pathology present, help determine the most appropriate therapy, and provide information relevant to graft prognosis.






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Online since 12th February '04
2004 - Journal of Postgraduate Medicine
Official Publication of the Staff Society of the Seth GS Medical College and KEM Hospital, Mumbai, India
Published by Wolters Kluwer - Medknow