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 SYMPOSIUM
Year : 2005  |  Volume : 51  |  Issue : 3  |  Page : 201-204

Human leptospirosis: Management and prognosis


First Department of Internal Medicine, School of Medicine, Ehime University, Ehime 791-0295, Japan

Correspondence Address:
Y Kobayashi
First Department of Internal Medicine, School of Medicine, Ehime University, Ehime 791-0295
Japan
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Source of Support: None, Conflict of Interest: None


PMID: 16333193

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As leptospirosis is a treatable disease, early diagnosis and prompt treatment are important for better prognosis. Early diagnosis depends on the knowledge of epidemiological factors, presenting features and use of appropriate laboratory tests. Early institution of appropriate antimicrobial therapy in combination with supportive therapy reduces the mortality from this disease. Leptospires are sensitive to a variety of antimicrobial agents, including penicillin, cephems, aminoglycosides, tetracyclines and macrolides. Of these antimicrobial agents, short-term treatment with streptomycin exterminates, leptospires. When penicillin, cephems, tetracylines and macrolides are used, long-term therapy with large doses may be required from the early stage of the disease until the appearance of antibodies.






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Online since 12th February '04
© 2004 - Journal of Postgraduate Medicine
Official Publication of the Staff Society of the Seth GS Medical College and KEM Hospital, Mumbai, India
Published by Wolters Kluwer - Medknow