Journal of Postgraduate Medicine
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Year : 2006  |  Volume : 52  |  Issue : 4  |  Page : 315-320

Malarial hepatopathy


1 Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh - 160012, India
2 Department of Hepatology, Post Graduate Institute of Medical Education and Research, Chandigarh - 160012, India

Correspondence Address:
A Bhalla
Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh - 160012
India
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Source of Support: None, Conflict of Interest: None


PMID: 17102560

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Jaundice is a common clinical presentation in severe malaria, seen in approximately 2.5% patients with falciparuminfection but hepatitis is unusual. Although hepatic dysfunction is unusual and hepatic encephalopathy is almostnever seen in malaria, yet, cases of hepatic dysfunction are being increasingly reported in patients with P.falciparum infection, from different parts of world. The extent of hepatocellular dysfunction varies from mildabnormalities in liver function tests to hepatic failure. Patients with hepatocellular dysfunction in malaria aremore prone to develop complications, but have a favorable outcome if hepatic involvement is recognized earlyand managed properly. It is important to meticulously look for hepatic dysfunction in patients with severemalaria, distinguish it from fulminant hepatic failure and manage it aggressively.






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Online since 12th February '04
2004 - Journal of Postgraduate Medicine
Official Publication of the Staff Society of the Seth GS Medical College and KEM Hospital, Mumbai, India
Published by Wolters Kluwer - Medknow