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 CLINICAL ARTICLE
Year : 2015  |  Volume : 61  |  Issue : 3  |  Page : 193-196

Pulmonary choriostoma in a case of tuberous sclerosis complex


1 Department of Pulmonary Medicine, ESI-Post Graduate Institute of Medical Sciences and Research (PGIMSR), Delhi, India
2 Department of Pathology, ESI-Post Graduate Institute of Medical Sciences and Research (PGIMSR), Delhi, India

Correspondence Address:
D Gothi
Department of Pulmonary Medicine, ESI-Post Graduate Institute of Medical Sciences and Research (PGIMSR), Delhi
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0022-3859.159426

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A 52 years old lady was diagnosed to have Tuberous Sclerosis Complex (TSC) on the basis of 2 major and one minor criterion. She had family history of similar complaints in her sister and two sons. There was involvement of kidney in the form of angiomyolipoma, skin in the form of facial angiofibroma and teeth with a dental pit. She had an unusual lung involvement in the form of multiple small choristomas. Choristoma was diagnosed on transbronchial lung biopsy and was present in the form of disorganised striated muscles. The reported pulmonary manifestations of TCS i.e. lymphangioleiomyomatosis (LAM) and multifocal micronodular pneumocyte hyperplasia (MMPH) are types of hamartomas. Hamartomas and choristomas are both types of disorganized tissue. 'Choristoma'of lung in TSC however is not reported. Clinopathological correlation of pulmonary hamartoma and choristoma, and treatment in TSC has been discussed.






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Online since 12th February '04
2004 - Journal of Postgraduate Medicine
Official Publication of the Staff Society of the Seth GS Medical College and KEM Hospital, Mumbai, India
Published by Wolters Kluwer - Medknow