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 CASE REPORT
Year : 2016  |  Volume : 62  |  Issue : 3  |  Page : 205-207

POEMS syndrome associated with plasmacytoma of the clivus: "Time discovers the truth"


1 Department of Rheumatology, Lourdes Hospital, Kochi, Kerala, India
2 Department of Neurology, Lourdes Hospital, Kochi, Kerala, India
3 Department of Pathology, Lourdes Hospital, Kochi, Kerala, India

Correspondence Address:
J Thomas
Department of Rheumatology, Lourdes Hospital, Kochi, Kerala
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0022-3859.166181

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Polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, and skin changes (POEMS) syndrome is characterized by the presence of a monoclonal plasma cell disorder, peripheral neuropathy, and one or more of the following features: Osteosclerotic myeloma, Castleman's disease (angiofollicular lymph node hyperplasia), increased levels of serum vascular endothelial growth factor (VEGF), organomegaly, endocrinopathy, edema, typical skin changes, and papilledema. [1] Solitary plasmacytomas most frequently occur in the bone but can also be found in soft tissues (extramedullary plasmacytoma). [2] We report a case that showed a rare association of POEMS syndrome with a plasmacytoma of the clivus.






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Online since 12th February '04
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Official Publication of the Staff Society of the Seth GS Medical College and KEM Hospital, Mumbai, India
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