Journal of Postgraduate Medicine
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Year : 1979  |  Volume : 25  |  Issue : 1  |  Page : 12-14  

Dual action of antimuscarinic agents on the intestinal smooth muscle

SRK Acharya1, Subba Rao2 
1 Department of Pharmacology. J.T.M. Medical College, Davengere 577 004, India
2 Professor of Pharmacology, Government Medical College, Bellary-583 102, India

Correspondence Address:
Subba Rao
Professor of Pharmacology, Government Medical College, Bellary-583 102
India

Propantheline, oxyphenonium, isoproponaide, epidosine, adiphe­nine and atropine were studied for their effect on the superfused infesting of guinea pig and rat. In small, concentrations, all drugs produced a contraction, which with increasing concentration, was Hocked. Occasionally, a contraction and a relaxation or vice versa was recorded. A partial antagonism and a potentiation on the action of acetylcholine (Ach) during recovery was observed. In very high concentrations, all drugs produced a graded contraction of intestine, except adiphenine which produced a sustained contraction. Some­ times, a contraction and a relaxation was also observed.


How to cite this article:
Acharya S, Rao S. Dual action of antimuscarinic agents on the intestinal smooth muscle.J Postgrad Med 1979;25:12-14


How to cite this URL:
Acharya S, Rao S. Dual action of antimuscarinic agents on the intestinal smooth muscle. J Postgrad Med [serial online] 1979 [cited 2019 Dec 7 ];25:12-14
Available from: http://www.jpgmonline.com/article.asp?issn=0022-3859;year=1979;volume=25;issue=1;spage=12;epage=14;aulast=Acharya;type=0


 
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