Journal of Postgraduate Medicine
 Open access journal indexed with Index Medicus & EMBASE  
     Home | Subscribe | Feedback  

ORIGINAL ARTICLE
[View FULLTEXT] [Download PDF
 
Year : 1990  |  Volume : 36  |  Issue : 1  |  Page : 5-8  

Effect of intravenous infusion of verapamil in patients of severe hypertension.

SK Verma, R Dosi, SK Kaushik, A Bordia 
 Department of Medicine (Cardiology), R.N.T. Medical College, Udaipur.

Correspondence Address:
S K Verma
Department of Medicine (Cardiology), R.N.T. Medical College, Udaipur.

Thirty patients with diastolic blood pressure of 120 mm Hg or more were administered a bolus dose of verapamil (0.15 mg/kg) followed immediately by an intravenous infusion at a rate of 0.005 mg/kg/min for one hour. The patients were monitored during this period and three hours following the discontinuation of the infusion. The systolic, diastolic and mean blood pressures before verapamil administration were 221.4 +/- 7.5, 134.3 +/- 2.7 and 163.4 +/- 4.1 mm Hg respectively, which decreased to 170.1 +/- 5.2, 99.1 +/- 3.7 and 122.8 +/- 3.6 mm Hg after intravenous bolus of verapamil. The fall in all the levels of blood pressure was significant (p less than 0.001) and was maintained at the lower levels throughout the infusion period and even three hours after discontinuation of the therapy. No untowards effects were observed and there was no significant change in heart rate and electrocardiogram. It, thus, proves to be an useful addition to the therapeutic armamentarium in the acute management of severe hypertension.


How to cite this article:
Verma S K, Dosi R, Kaushik S K, Bordia A. Effect of intravenous infusion of verapamil in patients of severe hypertension. J Postgrad Med 1990;36:5-8


How to cite this URL:
Verma S K, Dosi R, Kaushik S K, Bordia A. Effect of intravenous infusion of verapamil in patients of severe hypertension. J Postgrad Med [serial online] 1990 [cited 2020 Apr 5 ];36:5-8
Available from: http://www.jpgmonline.com/article.asp?issn=0022-3859;year=1990;volume=36;issue=1;spage=5;epage=8;aulast=Verma;type=0


 
Sunday, April 5, 2020
 Site Map | Home | Contact Us | Feedback | Copyright  and disclaimer