Journal of Postgraduate Medicine
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Year : 1993  |  Volume : 39  |  Issue : 4  |  Page : 183-6  

Biochemical changes in polymorphonuclear leucocytes in diabetic patients.

JM Sawant 
 Dept of Biochemistry, Seth GS Medical College, Parel, Bombay, Maharashtra.

Correspondence Address:
J M Sawant
Dept of Biochemistry, Seth GS Medical College, Parel, Bombay, Maharashtra.

A study on the functional ability of polymorphonuclear leucocytes (PMNL) indicates that the total lysosomal enzyme levels viz. Beta-glucuronidase, lysozyme, acid phosphatase and alkaline phosphatase were not altered in diabetics, compared to that in control subjects. However, the findings also reveal that the release of these lysosomal enzymes in response to a particulate stimulus is impaired in diabetics. This suggests that the bactericidal capacity of these cells, which are involved in phagocytosis, is impaired in diabetics, making them more vulnerable to infections.


How to cite this article:
Sawant J M. Biochemical changes in polymorphonuclear leucocytes in diabetic patients. J Postgrad Med 1993;39:183-6


How to cite this URL:
Sawant J M. Biochemical changes in polymorphonuclear leucocytes in diabetic patients. J Postgrad Med [serial online] 1993 [cited 2019 Dec 12 ];39:183-6
Available from: http://www.jpgmonline.com/article.asp?issn=0022-3859;year=1993;volume=39;issue=4;spage=183;epage=6;aulast=Sawant;type=0


 
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