Journal of Postgraduate Medicine
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Year : 2004  |  Volume : 50  |  Issue : 2  |  Page : 131-139  

Topical immunomodulators in dermatology

Sujay Khandpur, VK Sharma, K Sumanth 
 Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi - 110029, India

Correspondence Address:
Sujay Khandpur
Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi - 110029
India

Topical immunomodulators are agents that regulate the local immune response of the skin. They are now emerging as the therapy of choice for several immune-mediated dermatoses such as atopic dermatitis, contact allergic dermatitis, alopecia areata, psoriasis, vitiligo, connective tissue disorders such as morphea and lupus erythematosus, disorders of keratinization and several benign and malignant skin tumours, because of their comparable efficacy, ease of application and greater safety than their systemic counterparts. They can be used on a domiciliary basis for longer periods without aggressive monitoring. In this article, we have discussed the mechanism of action, common indications and side-effects of the commonly used topical immunomodulators, excluding topical steroids. Moreover, newer agents, which are still in the experimental stages, have also been described. A MEDLINE search was undertaken using the key words «DQ»topical immunomodulators, dermatology«DQ» and related articles were also searched. In addition, a manual search for many Indian articles, which are not indexed, was also carried out. Wherever possible, the full article was reviewed. If the full article could not be traced, the abstract was used.


How to cite this article:
Khandpur S, Sharma V K, Sumanth K. Topical immunomodulators in dermatology.J Postgrad Med 2004;50:131-139


How to cite this URL:
Khandpur S, Sharma V K, Sumanth K. Topical immunomodulators in dermatology. J Postgrad Med [serial online] 2004 [cited 2014 Apr 25 ];50:131-139
Available from: http://www.jpgmonline.com/article.asp?issn=0022-3859;year=2004;volume=50;issue=2;spage=131;epage=139;aulast=Khandpur;type=0


 
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