Journal of Postgraduate Medicine
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Year : 2008  |  Volume : 54  |  Issue : 3  |  Page : 214-216  

A trial design that generates only «SQ»«SQ»positive«SQ»«SQ» results

E Ernst, MS Lee 
 Complementary Medicine, Peninsula Medical School, Universities of Exeter and Plymouth, 25 Victoria Park Road, Exeter EX2 4NT, United Kingdom

Correspondence Address:
E Ernst
Complementary Medicine, Peninsula Medical School, Universities of Exeter and Plymouth, 25 Victoria Park Road, Exeter EX2 4NT
United Kingdom

In this article, we test the hypothesis that randomized clinical trials of acupuncture for pain with certain design features (A + B versus B) are likely to generate false positive results. Based on electronic searches in six databases, 13 studies were found that met our inclusion criteria. They all suggested that acupuncture is effected (one only showing a positive trend, all others had significant results). We conclude that the «SQ»A + B versus B«SQ» design is prone to false positive results and discuss the design features that might prevent or exacerbate this problem.


How to cite this article:
Ernst E, Lee M S. A trial design that generates only ''positive'' results.J Postgrad Med 2008;54:214-216


How to cite this URL:
Ernst E, Lee M S. A trial design that generates only ''positive'' results. J Postgrad Med [serial online] 2008 [cited 2019 Jun 26 ];54:214-216
Available from: http://www.jpgmonline.com/article.asp?issn=0022-3859;year=2008;volume=54;issue=3;spage=214;epage=216;aulast=Ernst;type=0


 
Wednesday, June 26, 2019
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