Journal of Postgraduate Medicine
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ORIGINAL ARTICLE
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Year : 2014  |  Volume : 60  |  Issue : 1  |  Page : 3-6  

Persistent arthralgia among Chikungunya patients and associated risk factors in Chennai, South India

V Ramachandran, P Kaur, K Kanagasabai, S Vadivoo, MV Murhekar 
 National Institute of Epidemiology (ICMR), R-127, Tamil Nadu Housing Board, Ayapakkam, Chennai, Tamil Nadu, India

Correspondence Address:
V Ramachandran
National Institute of Epidemiology (ICMR), R-127, Tamil Nadu Housing Board, Ayapakkam, Chennai, Tamil Nadu
India

Context: Chikungunya (CHIK) fever is viral disease characterized by joint pain for prolonged duration in various settings. However, there are no reports of long-term follow-up of the CHIK patients from India. Aims: We conducted a cohort study to describe the clinical manifestations, incidence of persistent arthralgia, and the associated risk factors among patients with CHIK identified during an outbreak in a suburb of Chennai, India. Materials and Methods: We conducted a retrospective cum prospective cohort study in Gowripet, Avadi, Chennai. We included all adult CHIK case patients identified during the outbreak. We conducted a nested case-control study to identify the risk factors for persistent arthralgia defined as a CHIK case experiencing arthralgia for more than 15 days from the date of onset of illness. We included all 81 patients and 81 randomly selected controls. Results: All 403 case patients had joint pain. Approximately 40% suffered joint pain for up to 1 month and 7% had it beyond 1 year. The most commonly affected types of joints were knee (96%), wrist (80%), and ankle (77%) joints. Regarding the number of types of joints affected, 36% had six types of joints, 23% had five types of joints, and 14% had three types of joints affected. The overall incidence of persistent arthralgia was 80%. High-grade fever, involvement of four or more types of joints, and joint swelling were significantly associated with persistent arthralgia. Conclusions: High prevalence of persistent arthralgia indicates the need for appropriate treatment strategies to reduce the severity and duration of joint pain.


How to cite this article:
Ramachandran V, Kaur P, Kanagasabai K, Vadivoo S, Murhekar M V. Persistent arthralgia among Chikungunya patients and associated risk factors in Chennai, South India.J Postgrad Med 2014;60:3-6


How to cite this URL:
Ramachandran V, Kaur P, Kanagasabai K, Vadivoo S, Murhekar M V. Persistent arthralgia among Chikungunya patients and associated risk factors in Chennai, South India. J Postgrad Med [serial online] 2014 [cited 2019 Dec 12 ];60:3-6
Available from: http://www.jpgmonline.com/article.asp?issn=0022-3859;year=2014;volume=60;issue=1;spage=3;epage=6;aulast=Ramachandran;type=0


 
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