Journal of Postgraduate Medicine
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Year : 2016  |  Volume : 62  |  Issue : 3  |  Page : 205-207  

POEMS syndrome associated with plasmacytoma of the clivus: «DQ»Time discovers the truth«DQ»

J Thomas1, BV Maramattom2, J Varghese3, PM Kuruvilla3 
1 Department of Rheumatology, Lourdes Hospital, Kochi, Kerala, India
2 Department of Neurology, Lourdes Hospital, Kochi, Kerala, India
3 Department of Pathology, Lourdes Hospital, Kochi, Kerala, India

Correspondence Address:
J Thomas
Department of Rheumatology, Lourdes Hospital, Kochi, Kerala
India

Polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, and skin changes (POEMS) syndrome is characterized by the presence of a monoclonal plasma cell disorder, peripheral neuropathy, and one or more of the following features: Osteosclerotic myeloma, Castleman«SQ»s disease (angiofollicular lymph node hyperplasia), increased levels of serum vascular endothelial growth factor (VEGF), organomegaly, endocrinopathy, edema, typical skin changes, and papilledema. [1] Solitary plasmacytomas most frequently occur in the bone but can also be found in soft tissues (extramedullary plasmacytoma). [2] We report a case that showed a rare association of POEMS syndrome with a plasmacytoma of the clivus.


How to cite this article:
Thomas J, Maramattom B V, Varghese J, Kuruvilla P M. POEMS syndrome associated with plasmacytoma of the clivus: "Time discovers the truth".J Postgrad Med 2016;62:205-207


How to cite this URL:
Thomas J, Maramattom B V, Varghese J, Kuruvilla P M. POEMS syndrome associated with plasmacytoma of the clivus: "Time discovers the truth". J Postgrad Med [serial online] 2016 [cited 2019 Dec 13 ];62:205-207
Available from: http://www.jpgmonline.com/article.asp?issn=0022-3859;year=2016;volume=62;issue=3;spage=205;epage=207;aulast=Thomas;type=0


 
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