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  Citation statistics : Table of Contents
   1996| April-June  | Volume 42 | Issue 2  
 
 
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PAPERS
In-vitro inhibition of antiplatelet autoantibodies by intravenous immunoglobulins and Rh immunoglobulins.
YS Mehta, SS Badakere
April-June 1996, 42(2):46-9
PMID:0009715299
Autoimmune thrombocytopenia (AITP) is caused by autoantibodies to platelet glycoprotein antigens. Intravenous immunoglobulin (i.v.IgG) and Rh immunoglobulin infusions have found great significance in the treatment of AITP patients not responding to corticosteroids and other modes of therapy. In our study, it was observed that immunoglobulins (i.v.IgG & Rh), and their Fab fragments inhibited the binding of antiplatelet autoantibodies to normal platelets, from 15.8 to 90.7% and 25.6 to 90.08% respectively; whereas, their Fc portion did not show any inhibition. The presence of specific anti-idiotypic antibodies to antiplatelet autoantibodies was established by using monoclonal antibodies to Glycoprotein IIb/IIa and Glycoprotein Ib/IX, as the specific idiotype source. The i.v.IgG and Rh immunoglobulin products reacted with the monoclonal antibodies, only through their Fab and not through the Fc portions, thereby confirming its specific anti-idiotype activity.
  12 7,050 116
CASE REPORT
Hemangiopericytoma of the kidney.
AI Sarela, AA Mavanur, ZF Soonawala, HK Shah, AP Desai, AB Samsi
April-June 1996, 42(2):50-50
PMID:0009715300
The diagnosis and management of a thirty year old male with a hemangiopericytoma of the kidney is reported.
  3 4,104 88
Meckel-Gruber syndrome associated with short limbed dwarfism.
NN Malguria, SA Merchant, KV Kiran, SL Verghese
April-June 1996, 42(2):55-6
PMID:0009715303
Antenatal detection of Meckel-Gruber Syndrome associated with short-limbed devarfism is described here. This association has not been previously reported.
  3 8,607 124
PAPERS
Comparative study of intrathecal pethidine versus lignocaine as an anaesthetic and a postoperative analgesic for perianal surgery.
LS Chaudhari, DG Kane, BB Shivkumar, SK Kamath
April-June 1996, 42(2):43-5
PMID:0009715298
100 patients with ASA risk I & II and undergoing perianal surgery were studied for anaesthetic effects and postoperative analgesia following either intrathecal pethidine or lignocaine. Saddle block was performed either with intrathecal pethidine 5% (50 mg/ml) 0.5 mg/kg or 1 ml of 5% lignocaine. Sensory and motor block postoperative analgesia, need for additional analgesia were studied. The onset of sensory and motor blockade with lignocaine was faster than pethidine. However the sensory and motor blockade lasted longer with pethidine. The duration of postoperative analgesia was 15.39 +/- 5.14 hours as against duration of postoperative analgesia with lignocaine which was 1.3 +/- 0.53 hours. Only 10% of patients in the pethidine group required intramuscular analgesic supplementation whereas 30% of patients in the lignocaine group required intramuscular analgesic supplementation.
  3 6,375 141
Results of Austin Moore replacement.
AP Jadhav, SS Kulkarni, SV Vaidya, MM Divekar, SP Suralkar
April-June 1996, 42(2):33-8
PMID:0009715296
Forty cases of Austin Moore Replacement done for transcervical fractures of the femur in patients were reviewed after a period of 12 to 48 months postoperatively (mean 26 mth). 30 cases (75%) had mild to severe pain of non-infective origin, starting as early as 6 months postoperatively. This was irrespective of the make, size or position (varus/valgus) of the prosthesis. Though the Aufranc and Sweet clinical scoring was satisfactory in 65% cases, radiological evidence of complications like sinking, protrusion, etc. were seen in majority of the cases. Calcar resorption was seen in 34 cases (85%) as early as 4 months postoperatively. Results of THR and bipolar replacement done for transcervical fractures in recent literature show 85% pain-free cases at 5 years. We feel that Austin Moore Replacement should be reserved for patients more than 65 years of age and those who are less active or debilitated because of other factors, because of increased acetabular wear with time in the younger individual. This is corroborated by unsatisfactory results in patients less than 65 years of age (p < 0.05).
  2 21,589 229
The role of estimation of the ratio of preoperative serum thyroglobulin to the thyroid mass in predicting the behaviour of well differentiated thyroid cancers.
AK Sharma, AK Sarda, TK Chattopadhyay, MM Kapur
April-June 1996, 42(2):39-42
PMID:0009715297
Although serum thyroglobulin (STg) is a useful tumour marker to detect the recurrence of tumour in well differentiated thyroid carcinoma, it has as yet not been reported to be of value in predicting the behaviour of thyroid cancer. In the present study of 20 patients, the measurement of preoperative Stg/thyroid mass has been utilised to find out Tg synthesizing capacity of the tumour. This ratio was significantly higher in the patients with follicular variety than in papillary thyroid carcinoma. It was significantly higher in the metastasis group than in the group of patients without metastasis. The patients with functioning metastasis had a higher than average value of this 'ratio' than those with non functioning metastasis, though the difference was not statistically significant. Despite the limitation of a small number of patients included in this study, it is possible to highlight the possible utility of preoperative Stg estimation as a tumour marker in categorization of the patients of carcinoma of the thyroid gland.
  2 6,548 114
CASE REPORT
Clival chordoma in an infant.
AA Goel, TD Nadkarni, MV Kirtane
April-June 1996, 42(2):51-3
PMID:0009715301
An unusual case of clival chordoma seen in a 7 month 16 day old infant is presented. The literature on this subject, clinical course of such tumours and the management strategy in paediatric age group is reviewed.
  1 8,108 110
Primary fallopian tube carcinoma.
SP Pardeshi, MM Kulkarni, VA Hishikar
April-June 1996, 42(2):59-61
PMID:0009715305
Although Fallopian tubes are frequently involved in benign gynaecological conditions, primary malignant involvement is rare, and because of its rarity, lack of diagnostic accuracy, nonpresenting symptoms and physical findings, primary fallopian tube carcinoma is seldom diagnosed before laparotomy. We are reporting one such rare case.
  1 10,872 137
Consecutive cerebellar and cerebral astrocytomas.
MG Bhatjiwale, DD Muzumdar, AA Goel, TT Patankar
April-June 1996, 42(2):62-4
PMID:0009715306
An unusual astrocytoma occurring in different anatomical compartments of the brain is reported. The child was operated upon for a cerebellar astrocytoma when he was eight-and-half years old. Seven years later, he was operated for a cerebral astrocytoma. The growth of the similar tumours at these two sites is analysed and literature on the subject is reviewed. The concept of multicentricity is emphasized.
  - 7,331 110
Allergic bronchopulmonary aspergillosis.
JL Oak, DR Yavgal, RR Chakore
April-June 1996, 42(2):53-5
PMID:0009715302
A 38 year old male was diagnosed to have allergic bronchopulmonary aspergillosis which responded remarkably to prednisolone therapy.
  - 6,128 115
Musculoaponeurotic fibromatosis of both bones of forearm.
HH D'Souza, DV Kulkarni, BB Patel, AA Shivraman
April-June 1996, 42(2):57-9
PMID:0009715304
Desmoplastic fibroma is a rare primary tumour of bone. When it does occur, the sites of predilection are the long bones. The following is a case report of desmoplastic fibroma involving both bones of forearm in a 12 year old boy with a review of literature.
  - 5,275 53
Online since 12th February '04
2004 - Journal of Postgraduate Medicine
Official Publication of the Staff Society of the Seth GS Medical College and KEM Hospital, Mumbai, India
Published by Wolters Kluwer - Medknow