Journal of Postgraduate Medicine
 Open access journal indexed with Index Medicus & ISI's SCI  
Users online: 909  
Home | Subscribe | Feedback | Reader Login
About Latest Articles Back-Issues Article Submission Resources Sections Etcetera Contact
 
  NAVIGATE here  
  ::   Search
  ::   Ahead of print
  ::   Current Issue
  ::   Submit Article 
  ::   Apply as Referee 
  ::   JPGM WriteCon 
  ::   Current Symposium 

 


Export selected to
Endnote
Reference Manager
Procite
Medlars Format
RefWorks Format
BibTex Format
  Access statistics : Table of Contents
   2014| January-March  | Volume 60 | Issue 1  
    Online since March 14, 2014

 
 
  Archives   Previous Issue   Next Issue   Most popular articles   Most cited articles
 
Hide all abstracts  Show selected abstracts  Export selected to
  Viewed PDF Cited
CASE REPORTS
Xanthoma disseminatum: A progressive case with multisystem involvement
AM Attia, OA Bakry, EE Mohamed
January-March 2014, 60(1):69-71
DOI:10.4103/0022-3859.128817  PMID:24625943
Xanthoma disseminatum (XD) is a rare, benign, non-Langerhans cell histiocytic disorder. The pathogenesis is not clear. It manifests with multiple, grouped, red-brown to yellow papules and nodules involving the skin, mucous membranes, and internal organs. We present a case of progressive XD in a 10-year-old male child. The patient presented with progressive, bilateral and symmetrical, reddish-brown, coalescent papules on the neck, around both eyes and all over his trunk and extremities. Skin lesions were accompanied by blurred vision and hoarseness of voice. Examination revealed xanthomatous infiltration of cornea, oral, pharyngeal, and laryngeal mucosae. The patient had diabetes insipidus that was diagnosed 2 years before the appearance of skin lesions. Medical treatment with corticosteroids (20 mg/day) and azathioprine (2 mg/kg/day) did not stop the disease progression.
  10,834 31 -
NARRATIVE REVIEWS
Diabetic peripheral neuropathy and its evaluation in a clinical scenario: A review
S Dixit, A Maiya
January-March 2014, 60(1):33-40
PMID:24625937
Diabetes mellitus is not only a clinical syndrome characterizing hyperglycemia, but is also a cause of debilitating problem known as peripheral neuropathy (PN). This review addresses the importance of diagnosing PN in a clinical setting as PN causes pain and discomfort in lower extremities, loss or absence of protective sensations in the lower extremities leading to balance problems, risk of foot ulcerations, and a reduced quality of life in adults with type 2 diabetes. A variety of modalities or methods are available to evaluate both subjective and objective measures of peripheral nerve functions, and have been discussed in detail in this review. It is of utmost importance to understand that evaluating PN as a routine practice in a simple way may also play a vitally important role in preventing foot ulcers or fall-related morbidity and mortality in adults with type 2 diabetes.
  10,056 68 -
ORIGINAL ARTICLES
Efficacy of pralidoxime in organophosphorus poisoning: Revisiting the controversy in Indian setting
I Banerjee, SK Tripathi, A Sinha Roy
January-March 2014, 60(1):27-30
DOI:10.4103/0022-3859.128803  PMID:24625936
Context: Poisoning with organophosphorus (OP) compounds constitutes a global public health problem. Standard treatment of OP poisoning involves use of atropine and pralidoxime. While efficacy of atropine is well-established, clinical experience with pralidoxime in management of OP poisoning is controversial. Aims: To explore the efficacy of add-on pralidoxime with atropine over atropine alone in the management of OP poisoning. Settings and Design: An open-label, parallel-group, randomized clinical trial was conducted in a tertiary care district hospital in West Bengal. Materials and Methods: Patients presenting with features of OP poisoning were randomly allocated to receive atropine or atropine-plus-pralidoxime. Efficacy was assessed by analyzing mortality, requirement for ventilator support and the duration of stay in hospital. Statistical analysis: Chi-square test was done to compare the efficacy parameters between the two groups. A two-tailed P-value <0.05 was considered as statistically significant. Results: During the study period, 150 patients were screened following which 120 patients were randomized to either of the treatment arms. Add-on pralidoxime therapy did not offer any appreciable benefit over atropine alone in terms of reducing mortality (18.33% (11/60) versus 13.33% (8/60)) and ventilator requirement (5% (3/60) versus 8.33% (5/60)). However, patients randomized in the add-on pralidoxime arm experienced longer duration of hospital stay (7.02 ± 1.12 days) than those receiving atropine-alone therapy (5.68 ± 1.87 days) (P < 0.001). Conclusion: The present study suggested that add-on pralidoxime with atropine therapy did not offer any appreciable benefit over atropine alone in management of OP poisoning. However, further trials are needed to explore different dosing regimens of pralidoxime in order to determine its efficacy in OP poisoning.
  8,668 49 3
NARRATIVE REVIEWS
Role of inhaled amphotericin in allergic bronchopulmonary aspergillosis
IS Sehgal, R Agarwal
January-March 2014, 60(1):41-45
DOI:10.4103/0022-3859.128806  PMID:24625938
Allergic bronchopulmonary aspergillosis (ABPA) is an immunological pulmonary disorder caused by immune reactions mounted against the ubiquitous fungus Aspergillus fumigatus. The disease clinically manifests with poorly controlled asthma, hemoptysis, systemic manifestations like fever, anorexia and weight loss, fleeting pulmonary opacities and bronchiectasis. The natural course of the disease is characterized by repeated episodes of exacerbations. Almost 30-40% of the patients require prolonged therapy, which currently consists of corticosteroids and anti-fungal azoles; both these agents have significant adverse reactions. Amphotericin B administered via the inhaled route can achieve a high concentration in the small airways with minimal systemic side-effects. Nebulized amphotericin B has been used in the management of invasive pulmonary aspergillosis. The aim of this review is to study the utility of inhaled amphotericin in ABPA.
  6,607 54 3
CASE REPORTS
Luffa echinata: Healer plant or potential killer?
S Giri, CR Lokesh, S Sahu, N Gupta
January-March 2014, 60(1):72-74
DOI:10.4103/0022-3859.128819  PMID:24625944
Bristly luffa (Luffa echinata), a member of the cucurbitaceae family is an Ayurvedic medicinal plant, which has been used in the traditional system of medicine for variety of symptoms. The active constituents like cucurbitacin, saponin, echinatin, β-Sitosterol, oleanolic acid and flavonoids have important pathophysiological effects on human body. However, there is no earlier published report of any toxicity on humans. We report a case of a 50-year-old gentleman, who presented with gastrointestinal bleeding, deranged liver function and shock following consumption of dried fruits of Luffa echinata soaked overnight in water. He had antral gastritis and duodenal erosions on upper gastrointestinal endoscopy and was managed conservatively and recovered completely.
  6,576 32 -
ORIGINAL ARTICLES
Persistent arthralgia among Chikungunya patients and associated risk factors in Chennai, South India
V Ramachandran, P Kaur, K Kanagasabai, S Vadivoo, MV Murhekar
January-March 2014, 60(1):3-6
DOI:10.4103/0022-3859.128795  PMID:24625931
Context: Chikungunya (CHIK) fever is viral disease characterized by joint pain for prolonged duration in various settings. However, there are no reports of long-term follow-up of the CHIK patients from India. Aims: We conducted a cohort study to describe the clinical manifestations, incidence of persistent arthralgia, and the associated risk factors among patients with CHIK identified during an outbreak in a suburb of Chennai, India. Materials and Methods: We conducted a retrospective cum prospective cohort study in Gowripet, Avadi, Chennai. We included all adult CHIK case patients identified during the outbreak. We conducted a nested case-control study to identify the risk factors for persistent arthralgia defined as a CHIK case experiencing arthralgia for more than 15 days from the date of onset of illness. We included all 81 patients and 81 randomly selected controls. Results: All 403 case patients had joint pain. Approximately 40% suffered joint pain for up to 1 month and 7% had it beyond 1 year. The most commonly affected types of joints were knee (96%), wrist (80%), and ankle (77%) joints. Regarding the number of types of joints affected, 36% had six types of joints, 23% had five types of joints, and 14% had three types of joints affected. The overall incidence of persistent arthralgia was 80%. High-grade fever, involvement of four or more types of joints, and joint swelling were significantly associated with persistent arthralgia. Conclusions: High prevalence of persistent arthralgia indicates the need for appropriate treatment strategies to reduce the severity and duration of joint pain.
  4,973 39 1
BRIEF REPORTS
Evaluation of normal abdominal aortic diameters in the Indian population using computed tomography
A Jasper, G Harshe, SN Keshava, G Kulkarni, E Stephen, S Agarwal
January-March 2014, 60(1):57-60
DOI:10.4103/0022-3859.128813  PMID:24625941
Objectives: The aim of this study was to establish normal diameters for the suprarenal and infrarenal abdominal aorta measured at T12 and L3 vertebral levels in the Indian population and to study the variation in aortic diameters with age, sex, height, weight, body mass index (BMI), and body surface area (BSA). Materials and Methods: One hundred and forty-two patients who underwent helical contrast-enhanced computed tomography (CT) scans of the abdomen for non-cardiovascular reasons were recruited.. The mean internal diameters of the suprarenal and infrarenal abdominal aorta (maximum anteroposterior and transverse diameter) were measured at T12 and L3 vertebral levels and tabulated according to various age groups for both men and women. Pearson correlation coefficient was used to evaluate the correlation between aortic diameters, height, weight, BSA, and BMI. Results: The mean diameters of the suprarenal and infrarenal abdominal aorta measured at T12 and L3 vertebral levels, in men were 19.0 ± 2.3 and 13.8 ± 1.9 mm and in women 17.1 ± 2.3 and 12.0 ± 1.6 mm, respectively. The aortic diameter progressively increased in caliber with increasing age of the patients and was smaller in women than men. A significant positive correlation was found in men between the suprarenal and infrarenal aortic diameters and weight, BSA, and BMI. In women, this correlation was significant in the infrarenal aorta but not in the suprarenal aorta. Conclusion: We obtained a set of normal values for the abdominal aorta in the Indian population. The aortic diameters correlated with age, gender, and body size of the patients as seen with previously published data in the Western population. A brief comparison of data between Indian and Western population showed that the values obtained were less than published elsewhere and hence, this should be considered while formulating intervention protocols.
  4,706 38 1
ORIGINAL ARTICLES
Health-related quality of life in patients with chronic obstructive pulmonary disease in North India
H Negi, M Sarkar, AD Raval, K Pandey, P Das
January-March 2014, 60(1):7-11
DOI:10.4103/0022-3859.128797  PMID:24625932
Background and Objectives: Chronic obstructive pulmonary disease (COPD) is a major health problem in India and constitutes an important cause of mortality and morbidity. A cross-sectional study was undertaken to assess health-related quality of life (HRQL) and its determinants in patients with COPD from India. Materials and Methods: A total of 126 patients (73.81% male) were enrolled using convenient sampling prospectively in this cross-sectional study. Eligible patients were assessed for socioeconomic status, anthropometric measures, COPD severity, dyspnea and health status using the Hindi version of St George's Respiratory Questionnaire (SGRQ). Linear regression model was used to examine the association between risk factors and HRQL score (a higher score indicating poorer HRQL), adjusting for age and sex. Results: The mean total score for SGRQ in the patients was 52.66 ± 12.89, indicating a marked impairment of HRQL. Impairment was associated with the severity of airway obstruction, but within each Global Initiative for Chronic Obstructive Lung Disease (GOLD) stage, the variation (SD) was wide [stage I: 47.8 ± 12.3 (n = 14); stage II: 49.28 ± 11.69 (n = 47); stage III: 53.47 ± 11.69 (n = 44); stage IV: 61.75 ± 14.14 (n = 21)]. A regression analysis showed that body mass index, forced expiratory volume in 1 s (FEV 1 ), dyspnea grade, and depression were associated with poor HRQL. Conclusion: HRQL of COPD patients was significantly impaired across stages. Marked impairment of HRQL was found even in patients with mild disease.
  4,448 51 1
Comparative evaluation of prophylactic use of pregabalin, gabapentin and diclofenac sodium for prevention of succinylcholine-induced myalgia: A randomized, double-blinded study
CK Pandey, ST Karna, M Tandon, VK Pandey, A Singh
January-March 2014, 60(1):16-20
DOI:10.4103/0022-3859.128801  PMID:24625934
Context: Succinylcholine a depolarizing muscle relaxant with rapid onset, predictable course and short duration of action is associated with myalgia. Aim: The aim of this study is to evaluate the efficacy of pregabalin, gabapentin and diclofenac on the incidence and severity of succinylcholine-induced myalgia. Settings and Design: Tertiary Care Teaching Hospital. Materials and Methods: A total of 120 patients undergoing laparoscopic cholecystectomy were randomly assigned into three groups: Pregabalin group received 150 mg of pregabalin, gabapentin group received 600 mg of gabapentin and diclofenac group received 100 mg of diclofenac sodium orally 2 h prior to surgery. Anesthesia was induced with fentanyl 3 μg/kg, propofol 2-2.5 mg/kg and succinylcholine 1.5 mg/kg and was maintained with oxygen with sevoflurane in the air and intermittent vecuronium bromide. A blinded observer recorded post-operative pain scores on visual analog scale at different time intervals and myalgia at 24 h. Post-operative pain relief was provided with fentanyl based patient-controlled analgesia. Fentanyl consumption in 24 h was recorded as a primary outcome. Statistical Analysis: Patients' characteristics and total fentanyl consumption were compared using one-way ANOVA followed by post-hoc test. Pain score was compared amongst the groups using Kruskal Wallis test. Results: The myalgia occurred in 15, 14 and 13 patients in pregabalin, gabapentin and diclofenac sodium group respectively (P > 0.85). Patients in diclofenac group had significantly higher fentanyl consumption (674.85 ± 115.58 μg) compared with pregabalin group (601.87 ± 129.57 μg) (95% confidence interval [CI] = 34.8-120.7) and gabapentin group (612.29 ± 105.12 μg) (95% CI = 14.9-170.5). However, there was no significant difference in fentanyl consumption between pregabalin and gabapentin groups (95% CI = −34.8-120.7). There was a significant difference in visual analog score at time points 12, 18 and 24 h among the study groups. Conclusion: Pre-treatment with pregabalin, gabapentin and diclofenac had equal efficacy in reducing the incidence and severity of succinylcholine-induced myalgia. However, pre-treatment with pregabalin and gabapentin decreased post-operative pain scores and fentanyl consumption.
  3,936 54 -
Medical professionalism from a socio-cultural perspective: Evaluating medical residents communicative attitudes during the medical encounter in Malaysia
K Ganasegeran, SAR Al-Dubai
January-March 2014, 60(1):12-15
DOI:10.4103/0022-3859.128799  PMID:24625933
Context: The practice of medicine requires good communication skills to foster excellent rapport in doctor patient relationship. Reports on communication skills learning attitude among medical professionals are key essentials toward improving patient safety and quality of care. Aims: We aimed to determine factors affecting communication skills learning attitudes among medical residents in Malaysia. Settings and Design: Cross-sectional survey, in a Malaysian public health hospital. Materials and Methods: A total of 191 medical residents across medical and surgical based rotations were included. We assessed the validated communication skills attitude scale among medical residents from different rotations. Statistical Analysis: Statistical Package of Social Sciences (SPSS®) (version 16.0, IBM, Armonk, NY) was used. Cronbach's alpha was used to test the internal consistency of the scale. Descriptive analysis was conducted for all variables. Bivariate analysis was employed across the socio-demographic variables. Results: Majority of the residents believed that communication skills training should be made compulsory in Malaysia (78.5%). Medical residents agreed that acquiring good communication skills is essential to be a good doctor. However, the majority cited time pressures for not being able to learn communication skills. Significant differences in communication skills learning attitude scores were found between Malays and Chinese. Conclusion: The majority of medical residents had a positive attitude toward communication skills learning. Socio-demographic factors influenced communication skills learning attitude among medical residents. Incorporating communicative skills modules during hospital Continuous Medical Education for medical residents is essential to cultivate communicative skills attitudes for effective doctor-patient relationship during the routine medical encounters.
  3,880 34 2
BRIEF REPORTS
Serum 25 hydroxyvitamin D profile after single large oral doses of cholecalciferol (vitamin D3) in medical staff in North India: A pilot study
L Priyambada, V Bhatia, N Singh, E Bhatia
January-March 2014, 60(1):52-56
DOI:10.4103/0022-3859.128812  PMID:24625940
Background: Vitamin D deficiency is widely prevalent in India and subjects who have almost no exposure to sunlight are severely deficient. Daily oral doses of cholecalciferol (vitamin D3) are costly as compared to stoss doses and further, take a long time for the serum levels to reach a plateau. Compliance to supplementation may also be better if a regimen involves single oral doses of vitamin D at specified intervals rather than daily doses. Evidence-based guidelines regarding the dosing and the frequency of dosing for prophylactic intermittent supplementation (stoss doses) in severely-deficient subjects are few. Materials and Methods: In a prospective intervention study, we serially assessed 30 asymptomatic healthy medical staff for serum 25-hydroxyvitamin D [25(OH)D] and parathyroid hormone (PTH); (a) at baseline; (b) monthly for 3 months after single oral 60,000 units (U) cholecalciferol; (c) monthly for 3 months after 120,000 (or 180,000 for those with elevated alkaline phosphatase) U cholecalciferol; and, (d) subsequently, at 3 months after a repeat dose of 60,000 U cholecalciferol by repeated measures analysis of variance. Results: The baseline serum 25(OH)D was 7.1 ± 5.4 ng/mL (< 10 ng/mL in 85% subjects) which increased to 18.7 ± 8.9 ng/mL at 1 month after 60,000 U of cholecalciferol (P < 0.001) and decreased to 11.1 ± 5.3 ng/mL by the 3 rd month. The higher dose of 120,000 (or 180,000) U increased mean 25(OH)D to 28.9 ± 9.9 ng/mL at the end of 1 st month, declining to 17.9 ± 4.9 ng/mL (P < 0.001) at 3 months. With the subsequent 60,000 U the serum 25(OH)D was 18.4 ± 3.9 ng/mL at 3 months. PTH showed a corresponding negative trend. No hypercalcemia was observed. Conclusions: Vitamin D deficiency is highly prevalent amongst medical staff in Northern India. An initial dose of 120,000-180,000 U of cholecalciferol is required to elevate 25(OH)D out of the deficiency range. Maintenance dose is needed at 2 months.
  3,789 33 1
CASE REPORTS
Beware of parotitis induced by iodine-containing contrast media
AK Kohat, K Jayantee, RV Phadke, R Muthu, V Singh, UK Misra
January-March 2014, 60(1):75-76
DOI:10.4103/0022-3859.128820  PMID:24625945
Carotid stenting is being increasingly used for revascularization of the moderate to severe carotid stenosis and thus its complications are increasingly being recognized. We report a rare complication of induced by iodine contrast in a patient undergoing carotid stenting. s. A 51 year old man after the second stenting developed multiple small infarcts in spite of the distal device. He also had painful parotid swelling which improved within a week. One should be aware of iodine parotitis s in the patients undergoing iodinated contrast study.
  3,776 33 1
LETTERS
Hypothyroidism, a rare cause of cerebellar folial calcification
B Sannananja, S Sankhe, H Shah, P Dabhade
January-March 2014, 60(1):92-93
DOI:10.4103/0022-3859.128832  PMID:24625954
  3,347 30 -
CASE REPORTS
Valgus deformity caused by dysplasia epiphysealis hemimelica in the knee
J Zhu, H Cheng, C Yang, Q Zhu
January-March 2014, 60(1):77-80
DOI:10.4103/0022-3859.128821  PMID:24625946
A rare case of dysplasia epiphysealis hemimelica in the left knee which caused valgus deformity and dysfunction of the limb is presented in this article. Subtotal excision of the lesion, distal femoral medial wedge osteotomy, and reconstruction of the medial collateral ligament were performed for treatment. Cannulated screws and plaster casts were used to stabilize the ligament and distal femur. Two years after removal and reconstruction, the knee was symptom free. The left knee laxity was restored and the mechanical axis of the distal femur was realigned.
  3,086 30 2
LETTERS
Posterior reversible encephalopathy syndrome in a patient of snake bite
B Varalaxmi, R Ram, P Sandeep, V Siva Kumar
January-March 2014, 60(1):89-90
DOI:10.4103/0022-3859.128830  PMID:24625952
  3,035 29 -
ORIGINAL ARTICLES
Patient-physician trust among adults of rural Tamil Nadu: A community-based survey
M Baidya, V Gopichandran, K Kosalram
January-March 2014, 60(1):21-26
DOI:10.4103/0022-3859.128802  PMID:24625935
Background: Trust is the acceptance of a vulnerable situation in which the truster believes that the trustee will act in the truster's best interests. The cornerstone of the patient-physician relationship is "trust". Despite the intensity and importance of trust relationship of patients toward their physician, the phenomenon is rarely studied in developing countries. Objective: Our study aimed to explore the concept of patient-physician trust among adults of rural Tamil Nadu to assess the factors affecting patient-physician trust relationship and patient satisfaction. Materials and Methods: A cross-sectional descriptive household survey was carried out on 112 individuals selected by a multistage random sampling method. Men and women aged above 40 years who have visited a health care service at least once during the last 5 years were included in the study. Thom et al's modification of the Anderson and Dedrick Physician Trust scale was used to measure patient trust in physician. Results: Trust is a one-dimensional construct in the surveyed population as revealed by an exploratory factor analysis which extracted one component explaining 50% of the overall variance. Trust influences patient's self-reported satisfaction (β coefficient of 0.048; P < 0.001) and remains independent of all the other factors assessed in the study such as, age, gender, education, self-reported health status, time spent with the physician, physician's gender, physician's age, and medical specialty that the physician belongs to. Physician's gender, physician's age, self-reported health status, and time spent with the physician were significantly associated with satisfaction with the physician. Conclusion: Trust in physicians seems to not depend on any of the assessed factors and largely seems to be implicit in the physician-patient relationship. Trust in physician is associated with patient satisfaction. Further studies are needed to assess trust in physicians in developing country settings.
  2,998 29 2
CASE REPORTS
Therapy-related acute promyelocytic leukemia following etoposide-based chemotherapy in non-seminomatous germ cell tumor
TN Kumar, Krishnamani , LV Gandhi, D Raghunadharao, G Sadashivudu
January-March 2014, 60(1):84-85
DOI:10.4103/0022-3859.128824  PMID:24625948
Therapy related AML (t- AML) accounts for 10-20% of all cases of AML. Cytotoxic agents implicated are alkylating agents, topoisomerase II inhibitors and rarely anti metabolites and anti tubulin agents. A growing incidence of therapy related acute promyelocytic leukemia (t-APL) has been reported over the last few decades in malignant and non malignant conditions. To the best of our knowledge this is the first t-APL case report to be reported in NSGCT post etoposide based therapy.
  2,696 32 1
CASE SERIES
Post ablation urethral stricture in posterior urethral valve
A Singh, M Bajpai, K Chand, A Ali
January-March 2014, 60(1):86-87
DOI:10.4103/0022-3859.128827  PMID:24625949
  2,616 26 -
ETHICS FORUM-RESEARCH ARTICLE
Projects not initiated by investigators: A retrospective analysis of the queries raised by the institutional ethics committees of a teaching hospital
SS Kuyare, PA Marathe, YC Shetty, SK Kamat, JV Katkar, UM Thatte
January-March 2014, 60(1):46-50
DOI:10.4103/0022-3859.128808  PMID:24625939
Background: Some investigators on receiving queries from Institutional Ethics Committee (IEC), either leave the queries unanswered or withdraw their studies. The present study was conducted to assess the queries raised by two IECs after reviewing studies that were not initiated and to identify reasons for the same. Clinical Trials Registry-India (CTRI) website was checked to review approval status of these studies at other sites. Materials and Methods: A retrospective analysis of studies (submitted between January 2006 and December 2011) not initiated by investigators on receiving queries from IECs were identified. The nature of of these studies: whether sponsored (pharmaceutical industry (pharma)/government/investigator initiated), single-centre/multi-centric, and queries raised were analyzed. Status of multi-centric trials; not initiated at our site was checked at CTRI. Data was analyzed using descriptive statistics. Results: A total of 219/2075 (11%) studies were not initiated. The proportions in pharma sponsored, investigator initiated, and government sponsored were 33%. 7.4%, and 8%, respectively. Out of a total of 1676 queries, the maximum queries were related to ethics (42%) and the least were administrative (7%). The largest proportion of queries in the pharma studies was ethical (47%), whereas majority were scientific queries (45.5%) for the investigator initiated studies. Twenty-one of the 94 multi-centric studies not initiated at our site were found registered at the CTRI and were ongoing or completed at 2-55 sites. Conclusion: Inability of investigators to defend studies due to lack of good clinical research practice (GCP) and research methodology training or unwillingness of sponsors to comply with local IEC requirements could be potential reasons for studies remaining uninitiated. Continued GCP training of investigators and IEC members and development of uniform ethical review standards across IECs are strongly recommended.
  2,501 33 1
GRAND ROUND CASE
A mysterious back pain
H Chen, D Gnepp, J Paul, S Borra
January-March 2014, 60(1):61-68
DOI:10.4103/0022-3859.128816  PMID:24625942
IgG4-related disease is a fibroinflammatory condition that affects many different organs. The common pathological findings of this disease include storiform fibrosis and dense infiltration of lymphocytes rich in IgG4-positive plasma cells. We herein presents the diagnosis and treatment of a case with a newly recognized condition - IgG4-related pachymeningitis.
  2,484 27 -
LETTERS
Comment on: Association of B12 deficiency and clinical neuropathy with metformin use in type 2 diabetes patients
MN Chowta, G Tiwary
January-March 2014, 60(1):96-97
PMID:24625957
  2,318 33 1
CASE REPORTS
Unusual way of loosened total hip arthroplasty treatment with an Austin Moore endoprosthesis
M Erceg, K Becic
January-March 2014, 60(1):81-83
DOI:10.4103/0022-3859.128823  PMID:24625947
A 65-year-old female patient with aseptic loosening of total cemented hip endoprosthesis and pathologic fracture of the femur at the level of the stem of endoprosthesis was presented. As no appropriate endoprosthesis was available due to the war in Croatia and war priority, the problem was managed by femur osteosynthesis and implantation of a partial Austin Moore hip endoprosthesis. The endoprosthesis is still functioning well (for 20 years).To the best of the author's knowledge, nobody has ever treated problem like this using this alternative, an unconventional method, with an Austin Moore endoprosthesis.
  2,306 28 -
LETTERS
Risk factors for drug induced hepatitis with first-line antituberculosis drugs in hospitalized patients of pulmonary tuberculosis
SM Pore, K Shinde
January-March 2014, 60(1):90-92
DOI:10.4103/0022-3859.128831  PMID:24625953
  2,294 31 -
Methanol poisoning with blindness and putaminal necrosis - was metabolic acidosis missed?
H Sanaei-Zadeh
January-March 2014, 60(1):88-88
DOI:10.4103/0022-3859.128828  PMID:24625950
  2,216 42 1
COMMENTARY
The efficacy of pralidoxime in organophosphorus poisoning: A commentary
JM Coulson
January-March 2014, 60(1):31-32
  2,223 29 -
LETTERS
Different epidemiology of candidemia in intensive care unit patients at a hospital in Taiwan
Wei-Lun Liu, Hsin-Lan Lin, Chih-Cheng Lai
January-March 2014, 60(1):88-89
DOI:10.4103/0022-3859.128829  PMID:24625951
  1,958 39 -
Comment: Association of B12 deficiency and clinical neuropathy with metformin use in type 2 diabetes patients
VN Shah
January-March 2014, 60(1):95-95
PMID:24625956
  1,850 35 1
Matching in case-control studies - A comment on, 'Do geriatrics require dose titration for antidiabetic agents?'
K Kaushal, SK Raina
January-March 2014, 60(1):93-94
DOI:10.4103/0022-3859.128833  PMID:24625955
  1,811 26 1
GUEST EDITORIAL
Dysplasia epiphysealis hemimelica: A diagnostic dilemma for orthopedic surgeons and a nightmare for parents
K Gökkus, AT Aydin
January-March 2014, 60(1):1-2
DOI:10.4103/0022-3859.128794  PMID:24625930
  1,581 26 -
ERRATUM
Erratum

January-March 2014, 60(1):99-99
DOI:10.4103/0022-3859.128840  PMID:24625958
  1,481 27 -
COMMENTARY
Commentary on projects not initiated by investigators: A retrospective analysis of the queries raised by the institutional ethics committees of a teaching hospital
A Jesani
January-March 2014, 60(1):51-51
  1,370 25 -
OBITUARY
In memoriam: Professor S Gopalakrishnan, M.Sc., Ph.D., M.B., B.S., 1940-2013
KG Krishnan
January-March 2014, 60(1):98-99
  1,352 35 -
LETTERS
Authors' reply
AK Singh, A Kumar, D Karmakar, RK Jha
January-March 2014, 60(1):97-97
  1,306 27 -
Authors' reply
AK Singh, A Kumar, D Karmakar, RK Jha
January-March 2014, 60(1):95-96
  1,225 31 -
Authors' reply
R Shastry, P Adhikari, A Kamath, MN Chowta, SD Ullal, MR Pai
January-March 2014, 60(1):94-95
  1,206 25 -
Online since 12th February '04
© 2004 - Journal of Postgraduate Medicine
Official Publication of the Staff Society of the Seth GS Medical College and KEM Hospital, Mumbai, India
Published by Wolters Kluwer - Medknow