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Figure 2: (a) Liver biopsy showed an altered architectural pattern with intrasinusoidal infiltration by spindle cell melanoma (H and E staining, original magnification ×40). (b) Spindled melanoma cells with melanin pigment (H and E staining, original magnification ×400). (c‑f) Malignant melanoma cells stained positively for HMB‑45 and S‑100 proteins and negatively for estrogen and progesterone receptors, respectively

Figure 2: (a) Liver biopsy showed an altered architectural pattern with intrasinusoidal infiltration by spindle cell melanoma (H and E staining, original magnification ×40). (b) Spindled melanoma cells with melanin pigment (H and E staining, original magnification ×400). (c‑f) Malignant melanoma cells stained positively for HMB‑45 and S‑100 proteins and negatively for estrogen and progesterone receptors, respectively