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| ARTICLE |
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| Year : 1977 | Volume
: 23
| Issue : 4 | Page : 161-167 |
Cephradine-a new cephalosporin in recurrent urinary tract infection
Vidya N Acharya, Kamini J Shroff, Neela H Mehta, KC Patel, Surangi K Jadav
Artificial Kidney Division Department of Medicine, Seth G. S. Medical College & K.E.M. Hospital, Parel, Bombay-400 012., India
Correspondence Address:
Vidya N Acharya
Artificial Kidney Division Department of Medicine, Seth G. S. Medical College & K.E.M. Hospital, Parel, Bombay-400 012.
India
 Source of Support: None, Conflict of Interest: None  | Check |
PMID: 615262 
Out of 866 bacterial isolates grown in significant colony counts from 3 consecutive mid-stream urine samples or from a single sample of urine obtained by suprapubic bladder puncture, 305 isolates (35.22%) were found to be sensitive to Cephradine. It was noted that Gram positive organisms (63.44%) manifested highest sensitivity to this antibiotic. Next in order was E. coli with a sensitivity of 60.54%. The clinical trial revealed a good response in 59.37% and 81.81; of patients with oral and injectable group respectively. The maximum response was seen in E. coli infections (89.47%) and Gram positive organisms coming next with 80% response. No major untoward reactions were noted in patients with or without azotaemia and the antibiotic could be used safely even in presence of renal failure.
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