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| ARTICLE |
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| Year : 1978 | Volume
: 24
| Issue : 1 | Page : 24-31 |
Comparison of the effects of feeding Indian fish liver oils supplemented with or without cholesterol and bile salts on certain enzymes in liver, heart and serum of rats
KG Tanksale, NG Magar
Department of Biochemistry and Nutrition, Seth G. S. Medical College, Parel, Bombay-400 012., India
Correspondence Address:
K G Tanksale
Department of Biochemistry and Nutrition, Seth G. S. Medical College, Parel, Bombay-400 012.
India
 Source of Support: None, Conflict of Interest: None  | Check |
PMID: 731609 
The enzymes viz. glucose-6-P-dehydrogenase (EC 1.1.1.49), cholesterol esterase (EC 3.1.1.13), aspartate amino transferase (EC 2.6.1.1) and alanine amino transferase (2.6.1.2) are intimately related to lipid metabolism. Hence their activities are bound to be affected by the type of dietary fat and substances like bile salts and cholesterol which also influence the lipid metabolism. This relationship between dietary lipid constituent and enzymes was studied in albino rats maintained on diets containing three Indian Shark Liver Oils viz. Waghbeer, Khada mushi and Pisori supplemented with or without cholesterol and bile salts, Enzyme activities were studied in liver, heart and serum. It was noted that higher unsaturation of dietary fat increased the activity of glucose-6-Pdehydrogenase enzyme while activities of transaminases and cholesterol esterase were lowered. Addition of cholesterol and bile salts to these diets decreased the activity of glucose-6-P-dehydrogenase and hydrolytic activity of cholesterol esterase. There was increase in the activities of transaminases and esterifying activity of cholesterol esterase due to supplementation with cholesterol and bile salts.
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