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| ARTICLE |
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| Year : 1979 | Volume
: 25
| Issue : 1 | Page : 52-56 |
Serum lactic dehydrogenase isoenzymes and serum hydroxy butyric dehydrogenase in myocardial infarction
DS Kanekar, PN Sawant, Saroj P Taskar
Cordiovascular and Thoracic Centre, K.E.M. Hospital and Seth G.S. Medical College, Parel, Bombay 400012, India
Correspondence Address:
D S Kanekar
Cordiovascular and Thoracic Centre, K.E.M. Hospital and Seth G.S. Medical College, Parel, Bombay 400012
India
 Source of Support: None, Conflict of Interest: None  | Check |
PMID: 458744 
Total serum lactate dehydrogenase activity in cases of myocardial infarct is difficult to interpret as abnormal values can occur in diseases of liver, kidney and skeletal muscle. The estimation of its isoenzymes is of better diagnostic help because of its tissue specificity. Serum LDH isoenzymes were studied in patients o f myocardial infarction and results are quantitated by densitometry. As LDH 1 represents serum hydroxybutyric dehydrogenase when 2-oxylbutyrate is used as substrate, serum hydroxybutyric dehydrogenase was also estimated in above patients. Greater specificity in diagnosis is achieved with SHBDH because of its myocardial nature and lower incidence of false positive results.
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