Journal of Postgraduate Medicine
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Year : 1994  |  Volume : 40  |  Issue : 2  |  Page : 92-3

Multiple myeloma presenting as proliferative (crescentic) glomerulonephritis.

Dept of Nephrology, Hinduja National Hospital, Mahim, Bombay.

Correspondence Address:
R A Sirsat
Dept of Nephrology, Hinduja National Hospital, Mahim, Bombay.

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Source of Support: None, Conflict of Interest: None

PMID: 0008737563

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Glomerular extracapillary cellular proliferation with crescent formation initially presenting as rapidly progressive glomerulonephritis is a rare clinical manifestation of multiple myeloma. We report here a case of a 58 year old female who initially presented with haematuria, loss of weight and appetite and history of febrile episodes and was diagnosed following renal biopsy as rapidly progressive glomerulonephritis. Haemodialysis was carried out a month later because of uremic symptoms and maintained with monitoring of serum, calcium, phosphate, alkaline phosphatase, albumin and iPTH levels. After 6 months, she complained of bone pains over anterior chest wall which persisted even with low calcium haemodialysis. Serum protein electrophoresis and bone marrow aspiration revealed multiple myeloma. On starting chemotherapy, bone pain subsided but the patient expired within 15 days of therapy.


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Online since 12th February '04
2004 - Journal of Postgraduate Medicine
Official Publication of the Staff Society of the Seth GS Medical College and KEM Hospital, Mumbai, India
Published by Wolters Kluwer - Medknow