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| PAPERS |
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| Year : 1994 | Volume
: 40
| Issue : 4 | Page : 202-3 |
Tinospora cordifolia induces colony stimulating activity in serum.
UM Thatte, SG Rao, SA Dahanukar
Dept of Pharmacology, Seth GS Medical College, Parel, Bombay, Maharashtra.
Correspondence Address:
U M Thatte
Dept of Pharmacology, Seth GS Medical College, Parel, Bombay, Maharashtra.
 Source of Support: None, Conflict of Interest: None  | Check |
PMID: 0009136239 
Tinospora cordifolia (Tc) is an Indian medicinal plant with proven immunomodulatory activity. This study was performed to elucidate its possible mechanism of action. We measured CFU-GM Cotony forming units of the granulocyte-macrophage series in serum of mice treated with Tc. We found that 10 days treatment with Tc (100 mg/ kg/d) induced a significant (p < 0.01) increase in the number of CFU-GM (255 +/- 49.32 vs 38.51 +/- 9.98) This suggests that activation of macrophages by Tc leads to increase in GM-CSF which leads to leucocytosis and improved neutrophil function.
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