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Year : 2001  |  Volume : 47  |  Issue : 1  |  Page : 52-3

Myxoid liposarcoma of the spermatic cord.

Department of General Surgery, Seth G.S. Medical College & K.E.M. Hospital, Parel, Mumbai - 400 012, India., India

Correspondence Address:
Y S Kashid
Department of General Surgery, Seth G.S. Medical College & K.E.M. Hospital, Parel, Mumbai - 400 012, India.
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Source of Support: None, Conflict of Interest: None

PMID: 11590296

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Keywords: Aged, Aged, 80 and over, Case Report, Genital Neoplasms, Male, diagnosis,pathology,surgery,Human, Liposarcoma, Myxoid, diagnosis,pathology,surgery,Male, Spermatic Cord,

How to cite this article:
Kashid Y S, Bakshi G K, Joshi A S, Mohite J D. Myxoid liposarcoma of the spermatic cord. J Postgrad Med 2001;47:52

How to cite this URL:
Kashid Y S, Bakshi G K, Joshi A S, Mohite J D. Myxoid liposarcoma of the spermatic cord. J Postgrad Med [serial online] 2001 [cited 2023 Jun 3];47:52. Available from:

An 80-year-old man presented with a rapidly increasing swelling in the left inguinoscrotal region of three months’ duration and a lump on the same side of lower abdomen, since two months.

On examination, the patient had hard, immobile, retroperitoneal lump continuous with left cord structures. Computerised tomographic (CT) scan showed a well defined inguinoscrotal mass of mixed density (soft tissue and fat attenuation) extending into pelvis and left side of retroperitoneum upto the lower pole of the left kidney, without associated lymphadenopathy. The diagnosis was liposarcoma of spermatic cord with extension into retroperitoneum. Search for metastases in lungs and liver did not reveal any.

At laparotomy, we found a large, well-encapsulated and hard tumour in the left retroperitoneum, pushing the bowel loops, bladder and left ureter towards right side and it was continuous with the left inguinoscrotal swelling. The testis was separate and normal. The aorta and IVC were free from the tumour. Complete excision of the retroperitoneal and inguino-scrotal tumour with left orchidectomy was done [Figure - 1].

Microscopically, it showed a highly cellular spindle cell tumour with variegated appearance showing fascicles, loose myxoid areas and poorly cellular areas. There were many multinucleate tumour giant cells, lipoblasts, stellate cells and compressed vascular channels. Frozen section and Oil Red O stain showed abundant fat in the tumour cells [Figure - 2]. Histopathological diagnosis was myxoid liposarcoma of the spermatic cord with extension into retroperitoneum.

In our patient though complete excision of the tumour was possible, we could not get wider margin for radical excision. Hence, the patient was advised postoperative radiotherapy. The patient had local recurrence and liver metastasis within three months and succumbed later.

  ::   Discussion Top

Myxoid liposarcoma is rarely found in the spermatic cord. It tends to occur in the elderly, presenting as painless scrotal swelling and is often confused with hydrocele or chronic incarcerated inguinal hernia.[1] Till 1997, only 14 cases of myxoid liposarcomas have been reported.[2] Of these one was a giant tumour weighing 42 kg.[3] This tumour may arise from the cord tissue representing extension of retroperitoneal fat or as malignant transformation of a preexisting lipoma. It generally behaves like a well differentiated liposarcoma.[1] CT scan is diagnostic of liposarcomas. Wide excision with orchidectomy is the treatment of choice for spermatic cord liposarcomas. Local recurrence is commoner than distant metastasis.[4] Retroperitoneal lymphadenectomy is not recommended as retroperitoneal lymph nodal spread is unlikely.[5],[6] Adjuvant radiotherapy is recommended in well-differentiated and myxoid type if local control is not complete. This may reduce the incidence of locoregional recurrence.[7] Benefit of chemotherapy is controversial.[4] Myxoid liposarcoma of the spermatic cord being a low grade, well-differentiated sarcomas it does not recur with a higher grade or in less-differentiated form.[1] Local recurrence is best treated by wide excision, but the prognosis is poor.[8]

 :: References Top

1. Mcfadden D. Myxoid liposarcoma of the spermatic cord. J Surg Oncology 1989; 40:132-134.  Back to cited text no. 1    
2.Ikinger U, Westrich M, Pietz B, Mechtersheimer G, Schmidt C. Combined myxoid liposarcoma and angiolipoma of the spermatic cord. Urology 1997; 49:635-637.  Back to cited text no. 2    
3.Yol S, Tavli S, Tavli L, Belviranli M, Yosunkaya A. Retroperitoneal and scrotal giant liposarcoma. Surgery Today 1998; 28:339-342.  Back to cited text no. 3    
4.Morotta J, Dardenne B, Beauduin M, Darimont M, Timmermans L, Schmitz A. Liposarcoma of the spermatic cord. Acta Urologica Belgica 1996; 64:37-41.  Back to cited text no. 4    
5.Blitzer PH, Dosoretz DE, Proppe KE, Shipley WU. Treatment of malignant tumours of spermatic cord. A study of 10 cases and review of literature. J Urol 1981; 126:611-614.  Back to cited text no. 5    
6.Enzinger FM, Weiss SW. Liposarcoma. In: Enzinger FM, Weiss SW, editors. Soft Tissue Tumours, 3rd ed. USA: Mosby; 1995; pp 431-466.  Back to cited text no. 6    
7.Fagundes MA, Zerman AL, Althausen AF, Coen JJ, Shipley WU. The management of spermatic cord sarcoma. Cancer 1996; 77:1873-1876.  Back to cited text no. 7    
8.Lauretti S, Cappa M, Emiliozzi P, Casareale P, Ianari A, Defido L. Retroperitoneal Liposarcoma. Minerva Chirurgica 1998; 53:77-81.   Back to cited text no. 8    


[Figure - 1], [Figure - 2]


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Online since 12th February '04
© 2004 - Journal of Postgraduate Medicine
Official Publication of the Staff Society of the Seth GS Medical College and KEM Hospital, Mumbai, India
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