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| CASE REPORTS |
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| Year : 2005 | Volume
: 51
| Issue : 4 | Page : 326-327 |
Primary anaplastic large cell lymphoma of central nervous system-A case report
A Rupani1, C Modi1, S Desai2, J Rege1
1 Department of Pathology, T. N. Medical College, B. Y. L. Nair Charitable Hospital, Mumbai, India
2 Tata Memorial Hospital, Mumbai, India
Correspondence Address:
A Rupani
Department of Pathology, T. N. Medical College, B. Y. L. Nair Charitable Hospital, Mumbai
India
 Source of Support: None, Conflict of Interest: None  | Check |
PMID: 16388180 
Central nervous system (CNS) involvement is extremely rare in anaplastic large cell lymphoma (ALCL). Primary ALCL of CNS on radiology is often misdiagnosed as tuberculosis. We report a fatal case of primary ALCL of CNS in a 17 year old male. He came with history of headache and left partial seizures. MRI showed a well- circumscribed lesion in the right fronto-parietal lobe eroding the skull bone. Biopsy showed large pleomorphic cells. Immunohistochemical stains showed positivity for CD30, CD43, EMA and ALK-1. In spite of radiotherapy and steroids, patient expired. Hence a high level of suspicion is essential for early diagnosis and for instituting appropriate treatment.
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