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Year : 2006  |  Volume : 52  |  Issue : 1  |  Page : 33-34

Does ramadan modify the circadian patterns?

1 Departments of Cardiology, Trakya University, Medical School, Edirne, Turkey
2 Departments of Endocrinology, Trakya University, Medical School, Edirne, Turkey

Correspondence Address:
A Altun
Departments of Cardiology, Trakya University, Medical School, Edirne
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Source of Support: None, Conflict of Interest: None

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How to cite this article:
Altun A, Ugur-Altun B. Does ramadan modify the circadian patterns?. J Postgrad Med 2006;52:33-4

How to cite this URL:
Altun A, Ugur-Altun B. Does ramadan modify the circadian patterns?. J Postgrad Med [serial online] 2006 [cited 2023 Mar 22];52:33-4. Available from:

During the month of Ramadan, adult Muslims abstain from drinking and eating daily between sunrise and sunset. Because this is Muslim lunar calendar, the timing of this month of fast changes each year and the duration of restricted food and beverage intake can vary from between 12 and 16 h. This change of meal schedule is accompanied with changes in sleep habits, such as delayed and shortened sleep periods, which may affect endocrine and neuroendocrine circadian patterns. Several cardiovascular parameters (i.e., heart rate, blood pressure, vascular tone, and coagulation-fibrinolysis) show circadian pattern. Several studies reported that autonomic activity and melatonin rhtyhmicity may be responsible for circadian patterns of cardiovascular parameters.[1],[2],[3] Changes of sleep habit in Ramadan affects autonomic activity and melatonin rhtyhmicity. The other negative effects may be that, during fasting patients with cardiovascular disease cannot consume medications, such as anti-ischemic, anti-platelet, anti-hypertensive drugs, and drugs of heart failure on time. Some patients may get admitted to the hospital with cardiovascular symptoms owing to failure of therapy.

However, some studies reported that Ramadan fasting does not increase acute coronary syndrome. The present study revealed increased acute myocardial infarction rate in fasting subjects. In addition, it first showed circadian presentation of these patients. This important finding supports Ramadan fasting, namely, changes of food intake and sleep habit, affects the circadian cardiovascular patterns owing to changes in autonomic activity and melatonin rhtyhmicity.

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1.Bogdan A, Bouchareb B, Touitou Y. Ramadan fasting alters endocrine and neuroendocrine circadian patterns. Meal-time as a synchronizer in human? Life Sci 2001;68:1607-15.  Back to cited text no. 1  [PUBMED]  [FULLTEXT]
2.Roky R, Houti I, Moussamih S, Qotbi S, Aadil N. Physiological and chronobiological changes during Ramadan intermittent fasting. Ann Nutr Metab 2004;48:296-303.   Back to cited text no. 2  [PUBMED]  [FULLTEXT]
3.Yaprak M, Altun A, Vardar A, Aktoz M, Ciftci S, Ozbay G. Decreased nocturnal synthesis of melatonin in patients with coronary artery disease. Int J Cardiol 2003;89:103-7.  Back to cited text no. 3  [PUBMED]  [FULLTEXT]

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Online since 12th February '04
2004 - Journal of Postgraduate Medicine
Official Publication of the Staff Society of the Seth GS Medical College and KEM Hospital, Mumbai, India
Published by Wolters Kluwer - Medknow