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Year : 2007  |  Volume : 53  |  Issue : 2  |  Page : 128-134

Polycystic ovary syndrome: A component of metabolic syndrome?

Dr. Mohan's Diabetes Specialties Centre and Madras Diabetes Research Foundation, Gopalapuram, Chennai, India

Correspondence Address:
V Mohan
Dr. Mohan's Diabetes Specialties Centre and Madras Diabetes Research Foundation, Gopalapuram, Chennai
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0022-3859.32217

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In 1935, Stein and Leventhal first described the polycystic ovary (PCO) as a frequent cause of irregular ovulation in women seeking treatment for subfertility. Although the initial management was surgical with wedge resection of ovary, the availability of radioimmunoassay and increased clinical use of ultrasound made it clear that many women had the ultrasound characteristics of PCO with or without the biochemical or clinical features of PCOS and therefore that PCO were not associated with a single syndrome. The association between increased insulin resistance and PCOS is a consistent finding in all ethnic groups. Obesity is a common factor in the majority of women with PCOS. It is postulated that a woman may be genetically predisposed to developing PCOS but it is only the interaction of environmental factors (obesity) with the genetic factors that results in the characteristic metabolic and menstrual disturbances. Weight loss, altered diet and exercise have been shown to be effective in the management of PCOS. Importance of early recognition, proper intervention, long-term monitoring and health implications needs more concern.


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Online since 12th February '04
2004 - Journal of Postgraduate Medicine
Official Publication of the Staff Society of the Seth GS Medical College and KEM Hospital, Mumbai, India
Published by Wolters Kluwer - Medknow