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LETTER
Year : 2008  |  Volume : 54  |  Issue : 2  |  Page : 169-170

Non-traumatic herniation of the liver in an asthmatic patient


1 Department of Respiratory Medicine, Clinical Research Centre, Vallabhbhai Patel Chest Institute, University of Delhi, New Delhi - 110 007, India
2 Department of Pathology, Clinical Research Centre, Vallabhbhai Patel Chest Institute, University of Delhi, New Delhi - 110 007, India
3 Department of Cardiorespiratory Physiology, Clinical Research Centre, Vallabhbhai Patel Chest Institute, University of Delhi, New Delhi - 110 007, India

Correspondence Address:
S K Chhabra
Department of Cardiorespiratory Physiology, Clinical Research Centre, Vallabhbhai Patel Chest Institute, University of Delhi, New Delhi - 110 007
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0022-3859.40794

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How to cite this article:
Gupta S, Kulshreshtha R, Chhabra S K. Non-traumatic herniation of the liver in an asthmatic patient. J Postgrad Med 2008;54:169-70

How to cite this URL:
Gupta S, Kulshreshtha R, Chhabra S K. Non-traumatic herniation of the liver in an asthmatic patient. J Postgrad Med [serial online] 2008 [cited 2020 Oct 20];54:169-70. Available from: https://www.jpgmonline.com/text.asp?2008/54/2/169/40794


Sir,

Diaphragmatic hernias are commonly classified as congenital or acquired (traumatic and non-traumatic). Non-traumatic herniation into the thoracic cavity containing the liver is extremely rare with only six cases documented so far. [1],[2],[3],[4] In view of the rarity of the lesion and its likely confusion with other causes of a pulmonary nodule including a malignancy, we present a case of non-traumatic herniation of the liver diagnosed in a 57-year-old female patient.

The patient was on treatment for severe bronchial asthma and underwent a computed tomography of chest for suspected coexistent bronchiectasis. While conforming bronchiectasis, the scan also showed a well-defined, non-calcified round opacity of uniform soft tissue density, about 4 cm in diameter, in the right lower zone adjacent to the right diaphragm situated in the posterior basal segment [Figure - 1]. Suspecting a malignancy, a CT-guided fine needle aspiration cytology (FNAC) was performed that revealed cohesive clusters of epithelial cells with increased nuclear-cytoplasmic ratio, single prominent central nucleolus and mild nuclear pleomorphism. The cells were large, polygonal with an abundant vacuolated and finely granular cytoplasm with lipofuschin pigment. The cells were PAS positive and diastase-negative indicating the hepatic origin of the lesion. Thus, ruling out a malignancy, a diagnosis of liver herniation was made. On CT, 1mm cuts were obtained that showed the lower end of the opacity to be continuous with the right diaphragm with a small gap in the latter [Figure - 2]. No active intervention was deemed necessary. Three years later, a repeat scan showed considerable reduction in the size of the lesion [Figure - 3].

In the present case, the diagnosis was established on CT by the location of the opacity and the visualization of a rent in the diaphragm, and the histopathological features of a normal liver cytology. A thoracotomy was thus avoided. None of the other reported cases were followed up to determine the course of the lesion. Reduction in size after three years in the present case shows that the hernia may undergo spontaneous regression. Thus, a diagnosis of liver herniation should be considered in the differential diagnosis of an intrathoracic opacity in the lower lobes of the lungs, especially if it is in contact with the diaphragm, along with primary lung, pleural and diaphragmatic neoplasms as well as metastases and other non-neoplastic causes. A noninvasive imaging modality such as a CT scan with FNAC should establish the correct diagnosis and more invasive procedures like diagnostic pneumoperitoneum and an exploratory thoracotomy should seldom be required.

 
 :: References Top

1.Poe HR, Schowengerdt GC. Two cases of atraumatic herniation of the liver. Am Rev Respir Dis 1972;105:195-63.  Back to cited text no. 1    
2.Epstein LR, Hall VR, Gillespie TJ, Hunt KK. Asymptomatic right lower thoracic nodule. Chest 1972;62:741-2.  Back to cited text no. 2    
3.Cosmo L, Nelson S, Haponik EF, Teaford TL, Summer WR. Nontraumatic hepatic diaphragmatic herniation: Demonstration by computed chest tomography. J La State Med Soc 1988;140:41-4.  Back to cited text no. 3  [PUBMED]  
4.Oshiro H, Kaneshima H, Kakau T, Fukuhara H, Nakamura H, Saito A. Liver herniation simulating a benign lung tumor. Nihon Kyoku Shikkan Gakkai Zasshi 1995;33:1155-9.  Back to cited text no. 4    


    Figures

  [Figure - 1], [Figure - 2], [Figure - 3]

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Online since 12th February '04
2004 - Journal of Postgraduate Medicine
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