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| CLINICAL SIGNS |
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| Year : 2008 | Volume
: 54
| Issue : 3 | Page : 238-240 |
Kayser-Fleischer ring
JC Suvarna
Department of Pediatrics, Seth GS Medical College and KEM Hospital, Mumbai, India
Correspondence Address:
J C Suvarna
Department of Pediatrics, Seth GS Medical College and KEM Hospital, Mumbai
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0022-3859.41816
Kayser-Fleischer (K-F) ring seen in Wilson's disease (WD) is due to copper deposition in the Descemet's membrane in the sclero-corneal junction. Although believed to be pathognomic of WD, it may be seen in many other hepatic conditions and intraocular copper-containing foreign bodies. The K-F ring detected in pre-symptomatic cases of WD may lead to speedy diagnosis and early management. Co-relation of K-F ring in WD to the disease severity, disappearance with successful treatment, reappearance with non-compliant treatment may aid in optimum management of WD. The importance of K-F ring detection in first-degree relatives of the index case cannot be over-emphasized.
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