Journal of Postgraduate Medicine
 Open access journal indexed with Index Medicus & ISI's SCI  
Users online: 6584  
Home | Subscribe | Feedback | Login 
About Latest Articles Back-Issues Articlesmenu-bullet Search Instructions Online Submission Subscribe Etcetera Contact
 ::   Next article
 ::   Previous article
 ::   Table of Contents

 ::   Similar in PUBMED
 ::  Search Pubmed for
 ::  Search in Google Scholar for
 ::Related articles
 ::   Citation Manager
 ::   Access Statistics
 ::   Reader Comments
 ::   Email Alert *
 ::   Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded249    
    Comments [Add]    
    Cited by others 8    

Recommend this journal


Year : 2009  |  Volume : 55  |  Issue : 2  |  Page : 108-112

Patient controlled sedation during central neuraxial anesthesia

1 Department of Anaesthesiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow - 226014, India
2 Department of Biostatistics, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow - 226014, India

Correspondence Address:
M Tripathi
Department of Anaesthesiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow - 226014
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0022-3859.52841

Rights and Permissions

Background: Patient controlled sedation (PCS) gives liberty to patients to choose the time of sedative administration to attain a desired level of comfort. Aims: The PCS use was evaluated in patients during surgery under central neuraxial blockade. Settings and Design: Prospective, cross-sectional, clinical study on consecutive patients in a tertiary care university hospital. Materials and Methods: PCS technique, using propofol (1%) 2 ml in 2 min was used in 160 adult patients undergoing urologic procedures under central neuraxial block. We observed the time to first PCS activation by patient, duration of surgery, propofol dose, sedation score, hemodynamic stability, patient's acceptability, and the factors correlating with the PCS use. Statistical analysis used: Non-parametric two-tailed Pearson's test, univariate correlation analysis for the factors favoring PCS use followed by multivariate logistic regression analysis amongst correlating factors. Results: In our cohort, the majority (83%) of the patients activated PCS during surgery under central neuraxial blocks at median time of 30 min and (17%) did not activate PCS. Female patients activated sedation earlier (median 15 min) than male patients (median 30 min). All patients were hemodynamically stable and without significant side effects. Multivariate analysis showed that sedative use significantly ( P <0.05) correlated with female gender (odds ratio-3.54 [IR-2.64 to 4.73]) and prolonged surgery (>90 min). Majority (91%) of patients rated PCS technique excellent to good. Conclusions: PCS was very well accepted by patients during central neuraxial block. Propofol regimen (2 ml in 2 min) in PCS was safe, as it caused neither apnea nor significant hypotension.


Print this article     Email this article

Online since 12th February '04
2004 - Journal of Postgraduate Medicine
Official Publication of the Staff Society of the Seth GS Medical College and KEM Hospital, Mumbai, India
Published by Wolters Kluwer - Medknow