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| CASE REPORT |
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| Year : 2013 | Volume
: 59
| Issue : 2 | Page : 131-134 |
Cerebral demyelination in children with collagenous colitis
S Sankararaman1, M Osman2, G Wellman3, SZ Hussain4
1 Department of Pediatrics, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA
2 Department of Pediatric Gastroenterology, Oklahoma University Health Sciences Center, Oklahoma City, Oklahoma, USA
3 Delta Pathology, Shreveport, Louisiana, USA
4 WK Pediatric Gastroenterology and Research, Willis-Knighton Hospital, Shreveport, Louisiana, USA
Correspondence Address:
S Z Hussain
WK Pediatric Gastroenterology and Research, Willis-Knighton Hospital, Shreveport, Louisiana
USA
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0022-3859.113848
Collagenous colitis (CC) is a form of microscopic colitis characterized by the presence of inflammatory infiltrate and subepithelial deposition of collagen in the colon and it is a rare condition with a predominant prevalence in the adult population. Only few cases have been reported in children. We report two children with the CC with concomitant neurological manifestations. Both cases demonstrated variable neurological symptoms clinically and significant cerebral demyelination. In both patients, the gastrointestinal manifestations drastically improved with a short course of prednisolone. However, the neurological symptoms were persistent and progressive. To the best of our knowledge, similar association has not been reported in children.
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