| CASE REPORT
|Year : 2016 | Volume
| Issue : 3 | Page : 205-207
POEMS syndrome associated with plasmacytoma of the clivus: "Time discovers the truth"
J Thomas1, BV Maramattom2, J Varghese3, PM Kuruvilla3
1 Department of Rheumatology, Lourdes Hospital, Kochi, Kerala, India
2 Department of Neurology, Lourdes Hospital, Kochi, Kerala, India
3 Department of Pathology, Lourdes Hospital, Kochi, Kerala, India
Polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, and skin changes (POEMS) syndrome is characterized by the presence of a monoclonal plasma cell disorder, peripheral neuropathy, and one or more of the following features: Osteosclerotic myeloma, Castleman's disease (angiofollicular lymph node hyperplasia), increased levels of serum vascular endothelial growth factor (VEGF), organomegaly, endocrinopathy, edema, typical skin changes, and papilledema.  Solitary plasmacytomas most frequently occur in the bone but can also be found in soft tissues (extramedullary plasmacytoma).  We report a case that showed a rare association of POEMS syndrome with a plasmacytoma of the clivus.
Department of Rheumatology, Lourdes Hospital, Kochi, Kerala
Source of Support: None, Conflict of Interest: None
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