|Year : 1985 | Volume
| Issue : 1 | Page : 57-8
Adamantinoma of tibia (a case report).
SS Surana, NK Mogra, MK Dube, AK Dhruva
S S Surana
|How to cite this article:|
Surana S S, Mogra N K, Dube M K, Dhruva A K. Adamantinoma of tibia (a case report). J Postgrad Med 1985;31:57-8
|How to cite this URL:|
Surana S S, Mogra N K, Dube M K, Dhruva A K. Adamantinoma of tibia (a case report). J Postgrad Med [serial online] 1985 [cited 2021 Sep 22 ];31:57-8
Available from: https://www.jpgmonline.com/text.asp?1985/31/1/57/5418
Adamantinoma of tibia is a rarely encountered neoplasm of dispute histogenesis and variable clinical course. Fischer found the microscopic similarity of the tumor with that of adamantinoma of jaw and labelled it as adamantinoma of tibia. The present case is described because of its rare occurrence.
Mrs. S.K., aged 35 years, was admitted at Jhunjhnu Hospital with gradually increasing, painful swelling in the lower half of left leg far the last 2 months. On examination, a painful swelling was found; It was about 4 x 2 x 1 cm in size, firm, tender and situated on the anterolateral aspect of the middle one-third of the left leg. The regional lymph nodes were not palpable. X-ray examination revealed a finely trabeculated, osteolytic lesion having well-defined margins in the shaft with osteosclerotic changes and the lesion was eccentrically situated.
Biopsy with currettage was done. On gross examination, the tumor was found to be grayish white and firm with attached fibromuscular tissue. On cutting, the tumour was found to be greyish-brown and homogenous with areas of cystic degeneration; foci of haemorrhage were present.
The microscopic examination revealed masses of epithelial like cells with minimal nuclear atypia, arranged in cords and islet formations, surrounded by dense fibrous stroma. The cells were slightly oval to spindle shaped; the cytoplasm was light pink and the cytoplasmic borders were distinct at places [Fig. 1]. Thus, a diagnosis of adamantinoma of tibia was made.
Adamantinoma of the long bones is an uncommon tumour arising from tibia, humerus, femur. ulna, fibula and capitate bones., Approximately 100 cases of admantinoma of the long bones have been reported so far.
Histological and electron microscopic studies confirm the epithelial origin of the tumour. Fisher proposed that the tumour arises from the misplaced nests of epithelial cells (enamel germ layer of teeth) during the early embryonic development. However, Dockerty and Meyerding suggested that implantation of cutaneous basal cells into bone as a result of trauma is the main factor. Further, Lichenstein considered it as a dermal inclusion tumour of the bone. Certain morphological and histochemical evidence supports its vascular origin., Because of the biphasic histological pattern, it was considered as a variant of synovial sarcoma. Vinogradova suggested its mesenchymal origin based on tissue culture studies.
The clinical course differs in many patients, as the tumor may behave as a benign or locally malignant entity. However, metastasis has also been reported., No evidence of regional or distant metastasis could be observed in the present case.
The treatment of choice is local resection, of the tumour. Simple currettage, as carried out in the present case, has a great risk of recurrence. Others prefer to do' amputation, to avoid the increased chances of metastasis in delayed untreated cases, specially looking to the malignant potentiality of the tumour.,
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