Journal of Postgraduate Medicine
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Year : 1986  |  Volume : 32  |  Issue : 3  |  Page : 120-1  

Mycoplasma and bad obstetric history.

AA Gogate, LL Deodhar, RR Bhatt 

Correspondence Address:
A A Gogate

How to cite this article:
Gogate A A, Deodhar L L, Bhatt R R. Mycoplasma and bad obstetric history. J Postgrad Med 1986;32:120-1

How to cite this URL:
Gogate A A, Deodhar L L, Bhatt R R. Mycoplasma and bad obstetric history. J Postgrad Med [serial online] 1986 [cited 2021 Mar 7 ];32:120-1
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The colonization of mycoplasma in the female genital tract is well known. Association of mycoplasma in cases of repeated abortions has been previously reported.[2],[3] In view of this, the study was undertaken to find out the association of mycoplasma in patients with repeated abortions.


A study group of 70 cases with more. than two pregnancy wastages and a control group of 50 cases without any bad obstetric history (B.O.H.) attending our antenatal clinic are included in this study.

Patient's cervical swab and urine were collected and were processed as described in our earlier publication.1 Identification of various micro-organisms was carried out by using standard tests.[5] Culture studies for chlamydia were not done.


[Table 1] shows the various organisms isolated from the study and control groups. There was no isolate of M. hominis, Group B streptococci or Chlamydia trachomatis (inclusion bodies only) in the control group. The isolation rate of U. urealyticum from the study group (17.1%) was much higher than from the control group (4%).

[Table 2] shows the correlation of foetal loss and mycoplasma isolation. Out of 70 cases, only 11 cases had history of first trimester losses. Only in one out of these 11, U. urealyticum was isolated. There were 25 cases of second trimester loss. Out of them in 5 cases, U. urealyticum and in 1 case, M. hominis were isolated. The maximum number of cases were in the 3rd trimester; and these had history of still birth after 30 weeks or neonatal loss. This group included 34 cases out of which, in 6 cases, U. urealyticum and in 2 cases, M. hominis were isolated.


Major chromosomal abnormalities and other genetic defects are responsible for a large proportion of first trimester losses whereas infections due to various organisms contribute to a large extent towards the second and third trimester pregnancy wastage.

Munday et al[4] have reported isolation of ureaplasma more often from the endometrium in women who had repeated spontaneous abortions as compared to the control group. The isolation rate of ureaplasma was much more than that of M. hominis. Our results are in concurrence with them.

As explained by Kundsin et al,[3] ureaplasma may be present at the time of conception and implantation and this whole process can be linked to unfavourable outcome of pregnancy.


1Bhatt, Manjiri; Deodhar, Leena; Gogate, Alka; Vaidya, Pratibha and Patel, M.V.: Mycoplasma in female genital tract. J. Postgrad. Med., 31: 112-114, 1985.
2Harwick, H.J., Purcell, R.L., Iuppa, J.B. and Fekety, F.R. Jr.: Mycoplasma hominis and abortion. J. Inf. Dis., 121: 260-268, 1970.
3Kundsin, R.B., Driscoll, S.G. and Pelletier, P.A.: Ureaplasma urealyticum incriminated in perinatal morbidity and mortality. Science, 213: 474-476, 1981.
4Munday, P.E., Porter, R., Falder, P.F., Carder, J.M., Holliman, R., Lewis, B.V. and Taylor-Robiason, D.: Spontaneous abortion-an infectious aetiology. Brit. J. Obstet. and Gynaecol., 91: 11771180, 1984.
5Sonnenwirth, A.C.: Collection and culture of specimens and guides for bacterial identification. In, "Gradwohl's Clinical Laboratory Methods and Diagnosis". 8th Edition, Editors: A.C. Sonnenwirth and L. Jarrette. The C.V. Mosby and Company, Saint Louis, Toronto and London, 1980, p. 1607.

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