Journal of Postgraduate Medicine
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Year : 1994  |  Volume : 40  |  Issue : 4  |  Page : 202-3  

Tinospora cordifolia induces colony stimulating activity in serum.

UM Thatte, SG Rao, SA Dahanukar 
 Dept of Pharmacology, Seth GS Medical College, Parel, Bombay, Maharashtra.

Correspondence Address:
U M Thatte
Dept of Pharmacology, Seth GS Medical College, Parel, Bombay, Maharashtra.

Tinospora cordifolia (Tc) is an Indian medicinal plant with proven immunomodulatory activity. This study was performed to elucidate its possible mechanism of action. We measured CFU-GM Cotony forming units of the granulocyte-macrophage series in serum of mice treated with Tc. We found that 10 days treatment with Tc (100 mg/ kg/d) induced a significant (p < 0.01) increase in the number of CFU-GM (255 +/- 49.32 vs 38.51 +/- 9.98) This suggests that activation of macrophages by Tc leads to increase in GM-CSF which leads to leucocytosis and improved neutrophil function.


How to cite this article:
Thatte U M, Rao S G, Dahanukar S A. Tinospora cordifolia induces colony stimulating activity in serum. J Postgrad Med 1994;40:202-3


How to cite this URL:
Thatte U M, Rao S G, Dahanukar S A. Tinospora cordifolia induces colony stimulating activity in serum. J Postgrad Med [serial online] 1994 [cited 2020 Nov 29 ];40:202-3
Available from: https://www.jpgmonline.com/article.asp?issn=0022-3859;year=1994;volume=40;issue=4;spage=202;epage=3;aulast=Thatte;type=0


 
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