Journal of Postgraduate Medicine
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Year : 2005  |  Volume : 51  |  Issue : 3  |  Page : 195-200  

Laboratory diagnosis of leptospirosis

SN Ahmad, S Shah, FM H Ahmad 
 Metropolis Health Services, Pvt Ltd, India

Correspondence Address:
F M H Ahmad
Metropolis Health Services, Pvt Ltd

Leptospirosis is a worldwide zoonosis caused by pathogenic Leptospira species, for which humans are accidental hosts. It is endemic in the tropical urban areas including our country, where seasonal epidemics are becoming increasingly common. Laboratory tests are necessary to confirm the diagnosis of clinically suspected leptospirosis due to its varied symptomatology. Moreover, leptospirosis must always be considered during the differential diagnosis of other tropical febrile illnesses .Laboratory analysis depends on the samples available and temporal stage of the illness. A confusing array of laboratory tests is described for the detection of this spirochete and antibodies. The conventional tests include direct microscopy, culture and the most widely used reference standard method -the microscopic agglutination test. In addition a variety of newer serological tests and those based on molecular techniques have been described.This review has attempted to describe the basis of these techniques and discussed the relative advantages and drawbacks of these assays with special emphasis on the selection of the most appropriate specimen and test, and the correct interpretation of the test result

How to cite this article:
Ahmad S N, Shah S, H Ahmad F M. Laboratory diagnosis of leptospirosis.J Postgrad Med 2005;51:195-200

How to cite this URL:
Ahmad S N, Shah S, H Ahmad F M. Laboratory diagnosis of leptospirosis. J Postgrad Med [serial online] 2005 [cited 2023 Sep 27 ];51:195-200
Available from:;year=2005;volume=51;issue=3;spage=195;epage=200;aulast=Ahmad;type=0

Wednesday, September 27, 2023
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