Journal of Postgraduate Medicine
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Year : 2008  |  Volume : 54  |  Issue : 2  |  Page : 135-137  

Hypereosinophilic syndrome with isolated Loeffler俟Q製 endocarditis: Complete resolution with corticosteroids

T Sen, CK Ponde, ZF Udwadia 
 Department of Pulmonology, PD Hinduja National Hospital and Medical Research Centre, Mahim, Mumbai - 400016, India

Correspondence Address:
Z F Udwadia
Department of Pulmonology, PD Hinduja National Hospital and Medical Research Centre, Mahim, Mumbai - 400016
India

Hypereosinophilic syndrome (HES) is classically defined as prolonged, unexplained peripheral eosinophilia in a patient presenting with evidence of end-organ damage. The heart is involved in two forms; endomyocardial fibrosis (Davies disease) and eosinophilic endocarditis (Loffler俟Q製 endocarditis). It was first reported in 1968 by Hard and Anderson. Chusid and co-workers formulated a definition with strict criteria for the diagnosis of HES as 1) peripheral blood eosinophilia more than 1500 cells/cu mm for at least six months duration 2)signs, symptoms of end-organ (heart, lungs, gastrointestinal tract, skin, bone-marrow, brain) involvement with eosinophil tissue infiltration/injury 3) exclusion of known secondary causes of eosinophilia. We report a case of hypereosinophilic syndrome with Loffler俟Q製 endocarditis, in the absence of endomyocardial fibrosis. The patient presented with a eosinophilic vegetation over the posterior leaflet of the mitral valve. There was complete resolution of the vegetation after two months of corticosteroid therapy.


How to cite this article:
Sen T, Ponde C K, Udwadia Z F. Hypereosinophilic syndrome with isolated Loeffler's endocarditis: Complete resolution with corticosteroids.J Postgrad Med 2008;54:135-137


How to cite this URL:
Sen T, Ponde C K, Udwadia Z F. Hypereosinophilic syndrome with isolated Loeffler's endocarditis: Complete resolution with corticosteroids. J Postgrad Med [serial online] 2008 [cited 2021 Feb 26 ];54:135-137
Available from: https://www.jpgmonline.com/article.asp?issn=0022-3859;year=2008;volume=54;issue=2;spage=135;epage=137;aulast=Sen;type=0


 
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