Journal of Postgraduate Medicine
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CASE REPORT
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Year : 2010  |  Volume : 56  |  Issue : 3  |  Page : 206-208  

Paradoxical embolism causing stroke and migraine

S Nightingale, GS Ray 
 Department of Cardiology, Wythenshawe Hospital, Southmoor Road, Wythenshawe, Manchester, United Kingdom

Correspondence Address:
S Nightingale
Department of Cardiology, Wythenshawe Hospital, Southmoor Road, Wythenshawe, Manchester
United Kingdom

This case report describes a lady who underwent investigations as a part of a clinical study. A 32-year-old woman with a history of episodes of severe migraine with aura, deep vein thrombosis and recurrent epistaxis, presented with two episodes of stroke with no particular cause evident on routine investigations. A contrast echocardiogram demonstrated a patent foramen ovale (PFO). She was found to be positive for the Factor V Leiden mutation. The PFO was closed percutaneously. However, a substantial right to left shunt of 14% persisted. Pulmonary angiography revealed multiple arterio-venous malformations (AVMs) and she was diagnosed with hereditary hemorrhagic telangiectasia. The AVMs were embolized and she has had no further cerebral events. Interestingly, her episodes of «SQ»migraine«SQ» have also improved dramatically following the closure of the PFO and the embolization of the AVMs. This case demonstrates the complex relationship between right to left shunts, cryptogenic stroke and migraine.


How to cite this article:
Nightingale S, Ray G S. Paradoxical embolism causing stroke and migraine.J Postgrad Med 2010;56:206-208


How to cite this URL:
Nightingale S, Ray G S. Paradoxical embolism causing stroke and migraine. J Postgrad Med [serial online] 2010 [cited 2021 Dec 8 ];56:206-208
Available from: https://www.jpgmonline.com/article.asp?issn=0022-3859;year=2010;volume=56;issue=3;spage=206;epage=208;aulast=Nightingale;type=0


 
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