Journal of Postgraduate Medicine
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Year : 2015  |  Volume : 61  |  Issue : 2  |  Page : 146  

Authors' reply

SK Sahu, S Giri, N Gupta 
 Department of Medicine, University College of Medical Sciences (UCMS), Delhi, India

Correspondence Address:
N Gupta
Department of Medicine, University College of Medical Sciences (UCMS), Delhi

How to cite this article:
Sahu S K, Giri S, Gupta N. Authors' reply.J Postgrad Med 2015;61:146-146

How to cite this URL:
Sahu S K, Giri S, Gupta N. Authors' reply. J Postgrad Med [serial online] 2015 [cited 2023 May 28 ];61:146-146
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We are happy that our manuscript is being read with great interest. I would like to address the queries raised on our manuscript. [1]

The role of steroids in transverse myelitis due to infection is controversial. Some studies have found IV methylprednisolone [2] to be useful while some studies have not. In view of the above reports, we planned to give IV methylprednisolone pulse along with antituberculous therapy.

There are reports of worsening of the existing symptoms or the appearance of new lesions in patients who initially respond well to the antituberculous therapy. [3],[4] However, none of our cases had such a paradoxical worsening clinically.

We also did not witness patients with transverse myelitis to have discitis, vertebral body involvement, or abscess.


1Ekinci S, Akyildiz F, Sari S, Akpancar S. Longitudinal extensive transverse myelitis due to tuberculosis: A report of four cases. J Postgrad Med 2015;61:145-6.
2Greenberg BM, Thomas KP, Krishnan C, Kaplin AI, Calabresi PA, Kerr DA. Idiopathic transverse myelitis: Corticosteroids, plasma exchange, or cyclophosphamide. Neurology 2007;68:1614-7.
3Moon MS, Moon YW, Moon JL, Kim SS, Sun DH. Conservative treatment of tuberculosis of the lumbar and lumbosacral spine. Clin Orthop Relat Res 2002;40-9.
4Cheng VC, Ho PL, Lee RA, Chan KS, Chan KK, Woo PC, et al. Clinical spectrum of paradoxical deterioration during antituberculosis therapy in non-HIV-infected patients. Eur J Clin Microbiol Infect Dis 2002;21:803-9.

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