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Erythrophagocytosis by blasts in a case of de novo acute monoblastic leukemia with rare but characteristic t(8;16)
A Gupta1, GK Reddy2, M Goyal1, MR Kasaragadda1
1 Department of Hematopathology and Genetics, AMPATH, Nallagandla, Serilingampally Hyderabad, Telangana, India
2 Department of Medical Oncology, Manipal Super Specialty Hospital, Vijaywada, Andhra Pradesh, India
Correspondence Address:
A Gupta
Department of Hematopathology and Genetics, AMPATH, Nallagandla, Serilingampally Hyderabad, Telangana
India
Erythrophagocytosis by leukemic blasts is a rare phenomenon. We report a case of a female diagnosed with acute monoblastic leukemia with leukemic blasts that were CD34 and CD117 negative, showing erythrophagocytosis, vacoulations, and a rare t(8;16) on bone marrow karyotype which is associated with a poor prognosis despite intensive chemotherapy. Meticulous bone marrow examination in such a scenario may point towards the presence of t(8;16) and help clinicians take a well-informed clinical decision.
How to cite this article:
Gupta A, Reddy G K, Goyal M, Kasaragadda M R. Erythrophagocytosis by blasts in a case of de novo acute monoblastic leukemia with rare but characteristic t(8;16).J Postgrad Med 2017;63:194-196
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How to cite this URL:
Gupta A, Reddy G K, Goyal M, Kasaragadda M R. Erythrophagocytosis by blasts in a case of de novo acute monoblastic leukemia with rare but characteristic t(8;16). J Postgrad Med [serial online] 2017 [cited 2023 Nov 29 ];63:194-196
Available from: https://www.jpgmonline.com/article.asp?issn=0022-3859;year=2017;volume=63;issue=3;spage=194;epage=196;aulast=Gupta;type=0 |
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