Journal of Postgraduate Medicine
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Year : 2021  |  Volume : 67  |  Issue : 1  |  Page : 29-32  

A case of premature and recurrent myocardial infarction associated with ABCA.1 gene mutation

K Subramaniam1, LA Babu2, N Shah3 
1 Department of Endocrinology, Silverline Hospital, Kochi, Kerala, India
2 Department of Medicine, Silverline Hospital, Kochi, Kerala, India
3 Neuberg Centre for Genomic Medicine, Ahmedabad, Gujarat, India

Correspondence Address:
K Subramaniam
Department of Endocrinology, Silverline Hospital, Kochi, Kerala
India

Coronary heart disease (CHD) is the most important cause of cardiovascular death and when premature, it affects the most productive population of the community. Premature CHD usually has a specific etiology, which on diagnosis, might help in the secondary prevention in that individual. We report a case of young adult with recurrent myocardial infarction, who on evaluation had mildly reduced HDL and Protein C levels with elevated serum homocysteine. Clinical exome identified a possibly pathogenic variant of ABCA1 gene, associated with Tangier disease.


How to cite this article:
Subramaniam K, Babu L A, Shah N. A case of premature and recurrent myocardial infarction associated with ABCA.1 gene mutation.J Postgrad Med 2021;67:29-32


How to cite this URL:
Subramaniam K, Babu L A, Shah N. A case of premature and recurrent myocardial infarction associated with ABCA.1 gene mutation. J Postgrad Med [serial online] 2021 [cited 2021 Apr 11 ];67:29-32
Available from: https://www.jpgmonline.com/article.asp?issn=0022-3859;year=2021;volume=67;issue=1;spage=29;epage=32;aulast=Subramaniam;type=0


 
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