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Figure 2: Changes in climacteric symptoms measured by the MRS I and subscores of three factors. MRS = Total score of MRS, INT = Intranasal estradiol, TTS = Transdermal estradiol, F1 = Factor 1 ‘hot flush’, F2 = Factor 2 ‘psyche’, F3 = Factor 3 ‘atrophy’, HF = MRS Item 1 (hot flushes). Values compared to baseline; *P < 0.05 for all measures, †P < 0.05 only at the end, and ‡P < 0.05 after 8 weeks of the treatment

Figure 2: Changes in climacteric symptoms measured by the MRS I and subscores of three factors. MRS = Total score of MRS, INT = Intranasal estradiol, TTS = Transdermal estradiol, F1 = Factor 1 ‘hot flush’, F2 = Factor 2 ‘psyche’, F3 = Factor 3 ‘atrophy’, HF = MRS Item 1 (hot flushes). Values compared to baseline; *P < 0.05 for all measures, †P < 0.05 only at the end, and ‡P < 0.05 after 8 weeks of the treatment