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Figure 1 :RFLP analysis for the 1298(A→C) mutation on a 163-bp PCR fragment with MboII. The 1298(A→C) abolishes an MboII restriction site. Digestion of the 163-bp fragment of the 1298AA genotype gives five fragments, of 56, 31, 30, 28 and 18 bp, whereas the 1298CC genotype results in four fragments, namely, 84, 31, 30, and 18 bp. The 18 bp fragment has been run off the gel

Figure 1 :RFLP analysis for the 1298(A→C) mutation on a 163-bp PCR fragment with MboII. The 1298(A→C) abolishes an MboII restriction site. Digestion of the 163-bp fragment of the 1298AA genotype gives five fragments, of 56, 31, 30, 28 and 18 bp, whereas the 1298CC genotype results in four fragments, namely, 84, 31, 30, and 18 bp. The 18 bp fragment has been run off the gel