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Figure 1: (a) gross image of a slice of splenic tissue showing a well-circumscribed tan-white lesion within the splenic parenchyma, without capsular breach; (b) relatively well-circumscribed tumor showing singly scattered atypical cells with scattered vascular formations - adjacent unremarkable splenic parenchyma is also seen (on left) (H and E stain, ×200); (c) high power view of the tumor demonstrates banal-looking cuboidal endothelial cells, some lining slit-like spaces - these cells show no cytologic/nuclear atypia or mitotic figures (H and E stain, ×200); (d-g) singly scattered endothelial cells along with vascular formation showing immunoreactivity for (d) vascular marker, CD31 (DAB ×400); (e) histiocytic marker, CD163 (DAB ×400); and (f) CD4 (DAB × 400); while negative for (g) CD8 (DAB ×400)

Figure 1: (a) gross image of a slice of splenic tissue showing a well-circumscribed tan-white lesion within the splenic parenchyma, without capsular breach; (b) relatively well-circumscribed tumor showing singly scattered atypical cells with scattered vascular formations - adjacent unremarkable splenic parenchyma is also seen (on left) (H and E stain, ×200); (c) high power view of the tumor demonstrates banal-looking cuboidal endothelial cells, some lining slit-like spaces - these cells show no cytologic/nuclear atypia or mitotic figures (H and E stain, ×200); (d-g) singly scattered endothelial cells along with vascular formation showing immunoreactivity for (d) vascular marker, CD31 (DAB ×400); (e) histiocytic marker, CD163 (DAB ×400); and (f) CD4 (DAB × 400); while negative for (g) CD8 (DAB ×400)